世界中医药Issue(2)：169-173,5.DOI:10.3969/j.issn.1673-7202.2015.02.005
中药内服外敷治疗肝硬化难治性腹水的疗效观察
Efficacy of Internal and External Treatment of Traditional Chinese Medicine for refractory ascites in liver cirrhosis patients
摘要
Abstract
Objective:To investigate the efficacy of oral traditional Chinese herbal of combination disease and syndrome and um-bilical compress with Xiaozhang Tie cataplasm in treating refractory ascites induced by liver cirrhosis.Methods:Eighty patients with cirrhosis and refractory ascites were randomly divided into two groups of equal size.The patients in control group were treated with primary therapy,while the test group took an oral traditional Chinese herbal of combination disease and syndrome and umbili-cal compress with Xiaozhang Tie cataplasm additionally.Efficacy was evaluated according to the criterion including ascites volume, body weight,abdominal circumference,urine 24-hour volume and major syndromes including abdominal distention,appetite,fla-tus and defecation.Results:Seventy-nine patients completed the study,1 were withdrawn.The two groups were comparable on baseline.Both groups showed decreased body weight and abdominal circumference,increased urine volume and improved symp-toms after treatment.However,the differences between pre-treatment and post-treatment in body weight,abdominal circumfer-ence,urine volume,abdominal distention,appetite and flatus were noticeably higher in the test group (n=39)than those in the control group (n=40).The effective rate of grade I and grade II was 52.5%for the test group and 25.0%for the control one (P<0.05 ).Conclusion:Traditional Chinese herbal of combination disease and syndrome and umbilical compress with Xiaozhang Tie cataplasm shows a remarkable adjuvant efficacy on refractory ascites induced by cirrhosis.关键词
肝硬化/难治性腹水/中药/病证结合/外治Key words
Cirrhosis/Refractory ascites/Traditional Chinese medicine/Combination disease and syndrome/External treatment分类
医药卫生引用本文复制引用
邢枫,陶艳艳,张华,赵长青,顾宏图,慕永平,袁继丽,周扬,刘成海..中药内服外敷治疗肝硬化难治性腹水的疗效观察[J].世界中医药,2015,(2):169-173,5.基金项目
国家自然科学基金项目（编号81473479）；上海市卫生局中医药科研基金 （）
