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系统药理学原理、方法及在中医药中的应用

张文娟 王永华

世界中医药Issue(2):280-286,7.
世界中医药Issue(2):280-286,7.DOI:10.3969/j.issn.1673-7202.2015.02.033

系统药理学原理、方法及在中医药中的应用

The Theory and Methods of Systems Pharmacology and Its Application in Traditional Chinese Medicine

张文娟 1王永华1

作者信息

  • 1. 西北农林科技大学生命学院生物信息学中心系统药理学实验室,咸阳,712100
  • 折叠

摘要

Abstract

Objective:To establish a scientific and effective research system for modern Chinese medicine.However,the current theory and measurement methods of systems analysis of TCM are still in its infant state.Methods:The new advances of system pharmacology (SP),its practical application in investigating the basic theory of TCM,optimization of old formulae and the discovery of new drugs were covered in this study.Results:Drug pharmacokinetics,efficacy,as well as systems biology were integrated into TCMSP.Conclusion:TCMSP will be a valuable tool to help the understanding of the interaction mechanism of TCM and human body at a systematic /molecular level,so as to guide the discovery of new drugs of TCM.

关键词

系统药理学/系统生物学/生物信息学/中药

Key words

Systems pharmacology/Systems Biology/Bioinformatics/Traditional Chinese Medicine

分类

医药卫生

引用本文复制引用

张文娟,王永华..系统药理学原理、方法及在中医药中的应用[J].世界中医药,2015,(2):280-286,7.

基金项目

国家科技支撑计划(编号2008BAI51B02),国家自然科学基金(编号31170796),国家重点基础研究发展计划(973计划)项目 ()

世界中医药

OACHSSCDCSTPCD

1673-7202

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