世界中医药Issue(4)：534-536,3.DOI:10.3969/j.issn.1673-7202.2015.04.016
丹红注射液治疗脑梗死患者的临床研究
Clinical Research of Dan Hong Injection for Treatment of Cerebral Infarction
祁涛 1彭吉霞 2刘兴林 2陈德森2
作者信息
- 1. 河南省平煤神马医疗集团总医院神经内科，平顶山，467099
- 2. 湖北医药学院机能实验室，十堰，442000
- 折叠
摘要
Abstract
Objective:To observe the clinical effects of Dan Hong Injection on cerebral infarction and to explore its action mecha-nism.Methods:A total of 202 patients with cerebral infarction were randomly divided into control group and treatment group.Con-trol group took oral aspirin and intravenous drip in adr + mannitol;the treatment group took Dan Hong Injection in addition to abovementioned treatments;after 2 weeks (W)treatment,we measured nitric oxide synthase (NOS)and superoxide dismutase (SOD)content,determined blood rheology indicators and regional cerebral blood flow (rCBF),nerve dysfunction scoring and com-pared the curative effect.Results:Compared with that of the control group),Dan Hong Injection could significantly increase SOD and NOS,improve rCBF and neural function defect score.Conclusion:Dan Hong Injection can decrease the lipid peroxidation after cerebral infarction,remove oxygen free radicals,improve regional cerebral blood flow,therefore have ideal efficacy on cerebral in-farction.关键词
丹红注射液/脑梗死/一氧化氮合成酶/超氧化物歧化酶/血液流变学/局部脑血流Key words
Dan Hong Injection/Cerebral infarction/Nitric oxide synthase/Superoxide dismutase/Hemorheology/Regional cerebral blood flow分类
医药卫生引用本文复制引用
祁涛,彭吉霞,刘兴林,陈德森..丹红注射液治疗脑梗死患者的临床研究[J].世界中医药,2015,(4):534-536,3.
