世界中医药Issue(6)：904-909,6.DOI:10.3969/j.issn.1673-7202.2015.06.026
4种复方丹参中药的精确分类及药效的理论评价
The Accurate Classification of Four Kinds of Compound Danshen Medicines and Theoretical Evaluation of Their Medical Efficiency
摘要
Abstract
Objective:To carry out accurate classification of four kinds of compound Danshen medicines and to propose the concept of accurate theoretical estimation of Chinese medicines’efficiency.Methods:Characteristic sequence of each sample was deter-mined relying on the dual index grade sequence individualized pattern recognition method,and the accurate identification of samples with similar composition of medicines was performed.Then the ratio of samples in correlation sequence of one sample’s characteris-tic sequence to the total samples,which belonged to the same class of the samples in the correlation sequence,was defined as the correlation degree parameter,in order to investigate theoretical approach for estimating efficiency of Chinese medicines with close composition.Results:The IR fingerprint spectra of 23 samples’components,belonging to four kinds of similar compound formulae containing Salvia miltiorrhiza,extracted with chloroform were measured,and were analyzed relying on dual index grade sequence in-dividualized pattern recognition method,and then their correlation degree analysis were carried out.As a result,these samples were accurately identified with the correct ratio is 96%.The correlation degrees among the four kinds of compound formulae were calcu-lated also,and it was found that for the two pairs of compound formula among the four kinds,their efficiency was directly proportion-al to their correlation degree.The results proved that dual index grade sequence individualized pattern recognition theory was suit-able to accurately identify many kinds of traditional Chinese compound formulae composed of very similar composition simultane-ously.Conclusion:The correlation degree may be a good parameter for theoretically evaluating the quality and medical efficiency of traditional Chinese compound formulae.关键词
药效关联度/精确鉴别/个性化模式识别/双指标/指纹图谱/复方丹参滴丸Key words
Medicine efficiency/Correlation degree/Compound Danshen dropping pills/Accurate identification/Individualized pattern recognition/Dual index/Fingerprint spectrum分类
医药卫生引用本文复制引用
邹华彬,王玲玲,杜爱琴,史培猛..4种复方丹参中药的精确分类及药效的理论评价[J].世界中医药,2015,(6):904-909,6.基金项目
山东省中医药科技发展计划项目 （）
