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从保护线粒体角度谈心肌缺血再灌注损伤

范宗静 吴旸 谢连娣 崔杰

世界中医药Issue(7):1124-1127,4.
世界中医药Issue(7):1124-1127,4.DOI:10.3969/j.issn.1673-7202.2015.07.041

从保护线粒体角度谈心肌缺血再灌注损伤

Study on Myocardial Ischemia Reperfusion Injury from the Perspective of Mitochondria Protection

范宗静 1吴旸 1谢连娣 1崔杰1

作者信息

  • 1. 北京中医药大学东方医院心内科,北京,100078
  • 折叠

摘要

Abstract

In recent years,studies have shown that mitochondria plays a role in several stages of myocardial ischemia reperfusion injury.Its main mechanism involves reactive oxygen,cell apoptosis and mitochondrial permeability transition pore opening.Tradi-tional Chinese medicine researches using mitochondria as target point have been given a lot of attention to in recent years.The arti-cle summarizes the mechanism of traditional Chinese medicine prevention of myocardial ischemia-reperfusion injury from the per-spective of protecting mitochondria.

关键词

中药/心肌缺血再灌注损伤/线粒体

Key words

Traditional Chinese Medicine/Myocardial ischemia reperfusion injury/Mitochondria

分类

医药卫生

引用本文复制引用

范宗静,吴旸,谢连娣,崔杰..从保护线粒体角度谈心肌缺血再灌注损伤[J].世界中医药,2015,(7):1124-1127,4.

基金项目

国家自然科学基金面上项目(编号81273692)---“黄芪多糖对缺血再灌注人心脏微血管内皮细胞凋亡及信号转导通路的影响”;国家自然科学基金青年基金项目(编号81102573)---“黄芪多糖对缺血再灌注损伤大鼠心肌线粒体 mPTP 开放及其调控因素的影响” ()

世界中医药

OACHSSCDCSTPCD

1673-7202

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