色谱Issue(5)：472-476,5.DOI:10.3724/SP.J.1123.2014.01042
固相萃取-超高效液相色谱-电喷雾串联质谱法同时测定地表水中16种全氟有机化合物
Simultaneous determination of sixteen perfluorinated organic compounds in surface water by solid phase extraction and ultra performance liquid chromatography with electrospray ionization tandem mass spectrometry
摘要
Abstract
A high-throughput detection method has been developed for the determination of six-teen perfluorinated organic compounds( PFCs)in surface water by solid phase extraction-ultra performance liquid chromatography coupled with electrospray ionization tandem mass spec-trometry( SPE-UPLC-ESI-MS/MS). The water samples were concentrated and purified through WAX solid phase extraction cartridges. The UPLC separation was performed on an ACQUITY UPLCTM BEH C18 column utilizing a gradient elution program of methanol(containing 2 mmol/L ammonium acetate)and water( containing 2 mmol/L ammonium acetate)as the mobile phases at a flow rate of 0. 4 mL/min. The MS/MS detection was performed under negative electrospray ionization( ESI-)in multiple reaction monitoring( MRM)mode. Good linearities were observed in the range of 0. 5-100 μg/L or 1. 0-100 μg/L with correlation coefficients from 0. 998 7 to 0. 999 9. The limits of detection( LODs)for the sixteen perfluorinated organic compounds were in the range of 0. 06-0. 46 ng/L. The recoveries ranged from 67. 6% to 103% with the relative standard deviations between 2. 94% and 12. 0%. This method was characterized by high sensitiv-ity and precision,extensive range and high speed,and can be applied for the analysis of PFC contaminants in surface water.关键词
固相萃取/超高效液相色谱/电喷雾串联质谱/全氟有机化合物/地表水Key words
solid phase extraction( SPE)/ultra performance liquid chromatography( UPLC)/electrospray ionization tandem mass spectrometry( ESI-MS/MS)/perfluorinated organic com-pounds/surface water分类
化学化工引用本文复制引用
张明,唐访良,俞雅雲,陈峰,徐建芬,叶永根..固相萃取-超高效液相色谱-电喷雾串联质谱法同时测定地表水中16种全氟有机化合物[J].色谱,2014,(5):472-476,5.基金项目
杭州市社会发展科研攻关项目（20130533B02）；杭州市环境保护科技项目（2013HZHB002）． （）
