色谱Issue(12)：1385-1389,5.DOI:10.3724/SP.J.1123.2014.09001
气相色谱-质谱／选择离子监测法用于苯乙烯不对称环氧化反应的筛选
Gas chromatography-mass spectrometry/selected ion monitoring for screening asymmetric epoxidation of styrene
摘要
Abstract
A screening method by gas chromatography-mass spectrometry( GC-MS)with selected ion monito-ring( SIM)has been developed for asymmetric epoxidation of styrene. All samples were analyzed by GC-MS with the mode of SIM by using ethylbenzene as the internal standard,by which styrene and styrene epoxide enantiomers were completely separated and their concentrations were accurately determined. Furthermore,this method was used to evaluate the epoxidation reaction of styrene,which was optimized by orthogonal experi-ment. The advantages of the method are as follows:excellent precision( RSD in the range of 1. 2%-5. 2%,n=5),good linearity( the correlation coefficients for styrene,( R)/( S)-styrene oxide were 0. 999 7,0. 993 2 and 0. 996 3,respectively),low limits of quantitation( LOQs of styrene,( R)/( S)-styrene oxide were 1. 3,1. 1 and 0. 7 mg/L,respectively)and reasonable recoveries( 98. 2%-108. 2%). All in all,the method provided a new way to determine the asymmetric epoxidation mixture of styrene and its homologs.关键词
气相色谱-质谱/选择离子监测/苯乙烯/环氧苯乙烷对映异构体/正交试验Key words
gas chromatography-mass spectrometry/selected ion monitoring(GC-MS/SIM)/styrene/styrene oxide enantiomers/orthogonal experiment分类
化学化工引用本文复制引用
牟瑶,韦思平,徐敏,陈平,王钦,杜曦..气相色谱-质谱／选择离子监测法用于苯乙烯不对称环氧化反应的筛选[J].色谱,2014,(12):1385-1389,5.基金项目
Sichuan Province Education Department Project（13ZB0263，13ZA0232）；Luzhou City Gov-ernment Project（2011-42）． （）
