色谱Issue(4):334-341,8.DOI:10.3724/SP.J.1123.2014.12041
涂层技术在毛细管电泳手性分离中的应用
Application of coating technology in capillary electrophoresis for chiral separation
摘要
Abstract
Chirality is one of the intrinsic attributes of the nature. Chiral separation and analysis are of great importance in many research fields, such as life science, environmental science, biological engineering and pharmaceutical engineering. Currently, chiral capillary electrophore⁃sis technique used for the enantioselective resolution of different kinds of racemates has become one of the most distinctive research and application fields. However, the adsorption of the analytes ( or chiral selectors) on the inner wall of the capillary is a common problem in cap⁃illary electrophoresis chiral separation. Coating technology, namely modification of the inner wall of the capillary, is the simplest and most effective way to suppress disadvantageous adsorption, and to improve the separation efficiency and analysis repeatability. In this review, the recent applications of different coating procedures in chiral analysis are presented, and the future developments in this field are also prospected.关键词
毛细管电泳/涂层/手性分离/综述Key words
capillary electrophoresis ( CE)/coating/chiral separation/review分类
化学化工引用本文复制引用
王丙香,柴微波,唐安娜,丁国生..涂层技术在毛细管电泳手性分离中的应用[J].色谱,2015,(4):334-341,8.基金项目
国家自然科学基金项目(21005054,21275081). ()