色谱Issue(4)：403-407,5.DOI:10.3724/SP.J.1123.2014.12045
聚（苯乙烯-co-甲基丙烯酸）自组装胶束假固定相电动色谱的特性
Electrokinetic chromatographic properties of amphiphilic copolymer poly (styrene-co-methacrylic acid) self-assembled micelle pseudostationary phase
摘要
Abstract
The amphiphilic copolymer poly ( styrene⁃co⁃methacrylic acid ) ( P ( St⁃co⁃MAA ) ) with molar ratios of 6∶4 and 7∶3 self⁃assembled to form micelles. The polymeric micelles were used as pseudostationary phase ( PSP ) in micellar electrokinetic chromatography ( MEKC ) . Their physicochemical properties and MEKC performance were investigated as well in the pres⁃ent work. The critical micelle concentration ( CMC ) , polarity, surface charge density and hydrodynamic diameter were used to characterize the solution physicochemical properties, while the methylene group selectivity was evaluated with n⁃alkylphenone homologous series. The time window and linear solvation energy relationship ( LSER) analysis were used to charac⁃terize the MEKC retention behavior and the selectivity. All of these were compared with poly ( methyl methacrylate⁃co⁃methacrylic acid ) ( P ( MMA⁃co⁃MAA ) ) with the molar ratio of 7∶3 and sodium dodecyl sulfate (SDS) micellar systems. The results showed that P(St⁃co⁃MAA) system had the minimum CMC, the widest time window and the best methylene group selectivi⁃ty . LSER analysis results showed that the hydrophobic effect was the most important interaction between solutes and PSPs, and the hydrogen⁃bonding acidity was the second significant factor on selectivity and MEKC retention behavior. P( St⁃co⁃MAA) system, especially with the molar ratio of 7∶3, had the highest effective parameter in LSER and showed a high separation selectiv⁃ity of PSP.关键词
胶束电动色谱/两亲性无规共聚物/假固定相/线性溶剂化能关系Key words
micellar electrokinetic chromatography (MEKC)/amphiphilic random copolymer/pseudostationary phase (PSP)/linear solvation energy relationships ( LSER)分类
化学化工引用本文复制引用
马新宇,倪鑫炯,卢婕,邢晓平,曹玉华,曹光群..聚（苯乙烯-co-甲基丙烯酸）自组装胶束假固定相电动色谱的特性[J].色谱,2015,(4):403-407,5.基金项目
国家自然科学基金项目（21174056，21405133）． （）
