色谱Issue(6)：571-576,6.DOI:10.3724/SP.J.1123.2015.03019
固相萃取-超高效液相色谱-串联质谱法同时测定食品接触塑料制品中10种苯并三唑类紫外吸收剂
Simultaneous determination of ten benzotriazole ultraviolet stabilizers in food contact plastic materials by solid phase extraction and ultra performance liquid chromatography with tandem mass spectrometry
摘要
Abstract
A sensitive method was developed for the simultaneous determination of ten benzo-triazole ultraviolet stabilizers in food contact plastic materials by ultra performance liquid chro-matography-tandem mass spectrometry( UPLC-MS/MS). The sample was extracted by metha-nol-dichloromethane,and purified by a C18 solid-phase extraction( SPE)column. The separa-tion was performed by using water containing 0. 1%( v/v ) formic acid and methanol as the mobile phases with gradient elution at a flow rate of 0. 3 mL/min. The electrospray ionization ( ESI)source in positive ion mode was used for the analysis of the ten benzotriazole ultraviolet stabilizers in multiple reaction monitoring( MRM)mode. The results showed that the standard curves were obtained with good correlation coefficients(r2﹥0. 996)in their linear concentration ranges. The limits of detection( LODs,S/N=3)for the ten benzotriazole ultraviolet stabilizers were in the range of 0. 6-1. 6 μg/kg. The mean recoveries for the ten benzotriazole ultraviolet stabilizers at three spiked levels( low,medium and high ) were 75. 2%-85. 3% with relative standard deviations of 1. 0%-5. 7%. Ten kinds of food contact plastic materials were tested,and 2,2′-methylenebis(6-(benzotriazol-2-yl)-4-tert-octylphenol)(UV-360)was found in a sample of polyethylene( PE ) material. The method is accurate,simple,rapid and feasible for the simultaneous determination of benzotriazole ultraviolet stabilizers in food plastic materials.关键词
超高效液相色谱-串联质谱/苯并三唑类化合物/紫外吸收剂/食品接触塑料制品Key words
ultra performance liquid chromatography-tandem mass spectrometry(UPLC-MS/MS)/benzotriazoles(BZTs)/ultraviolet stabilizers/food contact plastic materials分类
化学化工引用本文复制引用
勾新磊,赵新颖,池海涛,高峡,周明强,刘伟丽..固相萃取-超高效液相色谱-串联质谱法同时测定食品接触塑料制品中10种苯并三唑类紫外吸收剂[J].色谱,2015,(6):571-576,6.基金项目
北京市自然科学基金项目（2122018）；北京市科学技术研究院萌芽计划项目（2015-02）． （）
