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复方苦参注射液联合伊班膦酸钠治疗非小细胞肺癌骨转移癌疼痛的临床观察

占明 高宝安 王锡恩

生物加工过程Issue(1):206-208,3.
生物加工过程Issue(1):206-208,3.DOI:10.3969/j.issn.1673-7202.2015.02.014

复方苦参注射液联合伊班膦酸钠治疗非小细胞肺癌骨转移癌疼痛的临床观察

Clinical Observation on the Efficacy of Compound Matrine Injection Combined With Ibandronate in the Treatment of Cancer Pain in Patients with Non Small Cell Lung Cancer with Bone Metastasis

占明 1高宝安 1王锡恩2

作者信息

  • 1. 湖北省宜昌市中心人民医院呼吸内科,宜昌,443003
  • 2. 浙江省宁波市鄞州人民医院放化疗科,鄞州,315040
  • 折叠

摘要

Abstract

Objective:To investigate the effect of matrine injection combined with ibandronate clinical observation on treatment of non small cell lung cancer pain of bone metastasis.Methods:98 patients with non small cell lung cancer bone metastasis were re-cruited from 201 0 March to 201 2 March.According to their different ways of treatment,they were divided into control group and ob-servation group.The control group was treated with ibandronate treatment,the observation group were treated by compound matrine injection combined with ibandronate treatment.Efficacy,remission,and KPS score improvement were compared.Results:The near future curative effect in the results show that the partial remission cases (%)and the total effective rate of the observation group was obviously superior to the control group,and the difference was statistically significant (P<0. 05 ).Karnofsky score improve-ment cases (%)of the observation group is higher than that of the control group,and the difference was statistically significant (P<0. 05 ).Pain relief comparative analysis showed that complete remission cases (%)and the total remission rate of the observa-tion group was significantly superior to the control group,and the difference was statistically significant (P<0. 05 ).The incidence of adverse reactions had no significant difference between the two groups (P>0. 05 ).Conclusion:Compound matrine injection combined with ibandronate is significant in treating cancer pain in non small cell lung cancer bone,and can effectively reduce the pain of patients,thus is worthy of clinical application.

关键词

复方苦参注射液/伊班膦酸钠/非小细胞肺癌骨转移癌/中药治疗

Key words

Compound matrine injection/Ibandronate/Non small cell lung cancer bone metastasis/Treatment of Traditional Chinese Medicine

分类

医药卫生

引用本文复制引用

占明,高宝安,王锡恩..复方苦参注射液联合伊班膦酸钠治疗非小细胞肺癌骨转移癌疼痛的临床观察[J].生物加工过程,2015,(1):206-208,3.

基金项目

浙江省中医药科学研究基金计划 ()

生物加工过程

OACSTPCD

1672-3678

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