生物技术通报Issue(8)：132-137,6.
23株海洋真菌的分子鉴定及其抗植物病原真菌和细胞毒活性研究
Molecular Identification of 23 Marine Fungal Strains and Their Activities Against Plant Pathogenic Fungi and Cytotoxic Activities
摘要
Abstract
Twenty three marine fungal strains were isolated from the sediments of the South China Sea and identified by intergenic transcribed spacer(ITS)sequencing. The fermentation broth extracts of these marine fungal strains were tested for their inhibitory activities against growth of 4 plant pathogenic fungi, namely Colletotrichum gloeosporioides, Alternaria alternate, Curvularia lunata, Cylindrocladium scoparium, and investigated for their cytotoxic activities against SF-268, MCF-7, NCI-H460 and HepG-2 tumor cell lines by the SRB method. The results showed the extracts of 11 strains presented higher than 50%inhibitory rates against at least one of those plant pathogenic fungi at a concentration of 50 mg/mL and the extracts of 9 strains presented higher than 80%inhibitory rates against at least one of those tumor cell lines at a concentration of 100μg/mL. Among all strains studied, Eupenicillium sp. FS100, Penicillium sp. FS105, Dichotomomyces cejpii FS110 and Acaromyces ingoldii FS121 exhibited obvious inhibitory activities against plant pathogenic fungi and/or tumor cell lines.关键词
海洋真菌/分子鉴定/提取物/抗植物病原真菌/细胞毒活性Key words
Marine fungi/Molecular identification/Extract/Activity against plant pathogenic fungi/Cytotoxicity引用本文复制引用
杨小岚,陈玉婵,李浩华,章卫民..23株海洋真菌的分子鉴定及其抗植物病原真菌和细胞毒活性研究[J].生物技术通报,2014,(8):132-137,6.基金项目
国家自然科学基金项目（31272087），国家“863”计划资助项目（2012AA092104），广东省自然科学基金项目（S2013010014557），广州市科技计划项目 （）
