生物信息学Issue(1)：35-39,5.DOI:10.3969/j.issn.1672-5565.2015.01.07
基于PDB数据库的三个RNA二级结构预测软件评估
Evaluation of three RNA secondary structure prediction softwares based on PDB database
摘要
Abstract
With the development of molecular biology in the 21st century, the prediction of RNA secondary structure has become one of the most important contents in the field. Because the accuracy of RNA secondary structure prediction is crucial, it is very important to look for the secondary structure prediction tool with high precision and easy operation. In this article, three kinds of secondary structure prediction softwares were selected to evaluate their performances. Firstly, we predicted the RNA secondary structures of 318 RNA hairpins collected from PDB database, and then evaluated the performance of the softwares by comparing the predicted results with the experimental ones. Comparison results showed that RNA structure was superior to the other two kinds of softwares in predicting RNA secondary structure.关键词
RNA二级结构/PDB数据库/二级结构预测/准确性Key words
RNA secondary structures/PDB database/Secondary structure prediction/Accuracy分类
生物科学引用本文复制引用
刘伟,黄伊子,李都悦,向妍,周玮..基于PDB数据库的三个RNA二级结构预测软件评估[J].生物信息学,2015,(1):35-39,5.基金项目
国家自然科学基金青年项目（31301388）；中国博士后面上项目（2014M562109）；湖南省自然科学基金（14JJ3092）；湖南省科学技术厅科技计划项目（2014GK3046）；湖南农业大学大学生科技创新基金（团委）资助科研项目（18）；湖南农业大学植物保护学院＂大学生创新性实验计划项目（ SAY1106）。 （）
