生物信息学Issue(2)：77-81,5.DOI:10.3969/j.issn.1672-5565.2015.02.01
nc2Cancer：一个研究与癌症相关人类非编码RNA的数据库
nc2Cancer:a database for cancer-associated human ncRNAs
摘要
Abstract
With the rapid development of high⁃throughput sequencing technology, many new types of non⁃coding RNAs (such as lncRNAs and circular RNAs) have been identified. Previous studies have shown that these non⁃coding RNAs play critical roles in gene regulation and have strong associations with cancers. However, since we know little on how the ncRNAs excute their functions, it remains a challenge for us to fully identify the associations between ncRNAs and human cancer. To facilitate the study of this field, we analyzed large⁃scale RNA⁃RNA interaction data and constructed a database named nc2Cancer(http://www.bioinfo.tsinghua.edu.cn/nc2Cancer/index.php), a web resource which aims to provide comprehensive associations between ncRNAs and cancer. Currently, nc2Cancer covers three types of non⁃coding RNAs ( lncRNAs, circular RNAs and RNAs transcribed from pseudogenes) . This study will greatly expand the understanding of ncRNA functions and their possible roles in cancer development.关键词
非编码RNA/癌症/MicroRNA/RNA相互作用网络Key words
ncRNA/Cancer/microRNA/RNA-RNA network分类
信息技术与安全科学引用本文复制引用
程卓,刘珂,严章明,向书念,孙之荣..nc2Cancer：一个研究与癌症相关人类非编码RNA的数据库[J].生物信息学,2015,(2):77-81,5.基金项目
国家973计划（ No．2012CB925203），国家自然科学基金（ No．31171274）。 （）
