山西医科大学学报Issue(1)：1172-1176,5.DOI:10.13753/j.issn.1007-6611.2014.12.015
多巴酚丁胺负荷超声心动图检测病变冠状动脉的临床研究
Clinical research on dobutamine stress echocardiography for evaluating diseased coronary artery
杨青苗 1王国宏 1边红 1李洁 1王淑敏 1周岩1
作者信息
- 1. 首都医科大学附属北京同仁医院心血管疾病诊疗中心，北京100730
- 折叠
摘要
Abstract
Objective To investigate the regional wall motion abnormalities ( RWMA ) induced by dobutamine stress echocardio-graphy( DSE) for evaluating the diseased coronary artery,and thus providing the basis for the treatment and prognosis evaluation. Methods DSE and coronary angiography ( CAG ) were performed in 78 patients with clinically suspected coronary artery disease (CAD)to observe the location and scope of RWMA and calculate the wall motion score(WMS)and wall motion score index(WM-SI). Results The sensitivity of DSE for single lesion was 78. 05%,and the coincidence rate with CAG was 60. 98%. The sensitiv-ity of DSE was 81. 8% for detecting double branches lesions and 100% for three branches lesions. The coincidence rate with CAG was 35. 29% for detecting the multivessel lesions. The sensitivity of DSE was 65. 8%,26. 1% and 66. 1% for detecting LAD,LCX and RCA,respectively(P<0. 01),while there was no significant difference in specificity and accuracy(P>0. 05). There was signif-icant difference in WMSI at DSE peak load between CAD group and normal control group(P<0. 01),and there was no significant difference in RWMA between single and multiple lesions at DSE peak load(P=0. 147). Conclusion DSE has higher sensitivity and specificity to detect the RWMA in CAD patients and is a noninvasive method to estimate lesions of coronary artery. The sensitivi-ties to RCA and LAD are higher than that of LCX,and that is of great significance for clinical screening of CAG. The semi-quantita-tive WMS and WMSI values can indicate the level of left ventricular systolic function, but could not distinguish single lesion from multivessel lesions.关键词
超声心动图/多巴酚丁胺负荷/节段性室壁运动异常/冠心病/冠状动脉造影术Key words
echocardiography/dobutamine stress/regional wall motion abnormality/coronary artery disease/coronary angi-ography分类
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杨青苗,王国宏,边红,李洁,王淑敏,周岩..多巴酚丁胺负荷超声心动图检测病变冠状动脉的临床研究[J].山西医科大学学报,2015,(1):1172-1176,5.
