山西医科大学学报Issue(3)：256-258,3.DOI:10.13753/j.issn.1007-6611.2015.03.016
多靶点治疗老年肾病综合征的临床分析
Clinical analysis of multi-targets therapy in treatment of elderly nephrotic syndrome
摘要
Abstract
Objective To investigate the clinical efficacy of multi-targets therapy in treatment of elderly nephrotic syndrome. Methods Sixty-three elderly nephrotic syndrome patients in our hospital from May 2012 to May 2014 were randomly divided into the multi-target group and control group. Patients in multi-target group were treated with prednisone, mycophenolate mofetil( MMF) , tacrolimus, while patients in control group were treated with prednisone and cyclophosphamide. Clinical efficacy, urine and blood biochemical indexes were estimated after 3-month treatment. Results After 3-month treatment, the total effective rate in multi-target group was 96. 88%(31/32), significantly higher than in control group(83. 87%,P<0. 05). The urinary protein,serum creatinine,cholesterol and serum albumin were significantly improved in multi-target group compared with control group(P<0. 05). The recurrence rates and incidences of side effects were significantly lower in multi-target group than in control group(P<0. 05). Conclusion The clinical efficacy of multi-targets therapy in treatment of elderly nephrotic syndrome is significant.关键词
多靶点治疗/肾病综合征/老年人Key words
multi-target therapy/nephrotic syndrome/aged分类
医药卫生引用本文复制引用
马力群,王莉,段朝阳,马小琴,付荣国..多靶点治疗老年肾病综合征的临床分析[J].山西医科大学学报,2015,(3):256-258,3.基金项目
陕西省自然科学基金资助项目(2013JQ4024) （2013JQ4024）
陕西省科技攻关基金资助项目(2012K16-08-04) （2012K16-08-04）
