现代检验医学杂志Issue(5):49-53,57,6.DOI:10.3969/j.issn.1671-7414.2014.05.010
2012年河北地区临床分离细菌分布及耐药性监测
Surveillance of Antimicrobial Resistance and Pathogen of Clinical Isolates in Hebei Province in 2 0 1 2
时东彦 1赵文申 2陈玉兰 3郭映辉 4冯军花 5张征 6田卫 7徐晖 8李书君 9谢爽 10刘金禄 11赵建宏 1李继红 1曹丽军 12董爱英 13孙艳 14王迁 15刘建伟 16张敏17
作者信息
- 1. 河北医科大学第二医院检验科,河北省临床检验中心,石家庄050000
- 2. 邯郸市中心医院,河北邯郸 056001
- 3. 廊坊市人民医院,河北廊坊 065000
- 4. 河北省儿童医院,石家庄 050030
- 5. 河北医科大学第四医院,石家庄 050011
- 6. 河北医科大学第一医院,石家庄 050035
- 7. 唐山市工人医院,河北唐山 063000
- 8. 唐山市中医医院,河北唐山 063000
- 9. 邢台市人民医院,河北邢台 054001
- 10. 邢台医学高等专科学校第二附属医院,河北邢台 054000
- 11. 北方学院第一附属医院,河北张家口 075061
- 12. 河北大学附属医院,河北保定 071000
- 13. 河北联合大学附属医院,河北唐山 063000
- 14. 沧州市中心医院,河北沧州 061014
- 15. 沧州市人民医院,河北沧州 061000
- 16. 承德市中心医院,河北承德 067000
- 17. 承德医学院附属医院,河北承德 067000
- 折叠
摘要
Abstract
Objective To investigate antimicrobial resistance and pathogen in hebei antibacterial resistance investigation net in 2012.Methods Antimicrobial susceptibility test was detected by Kirby-Bauer method or broth dilution test.Results were analyzed according to CLSI 2010 breakpoints.WHONET 5.5 software was used to analyze the data.Results A total of 10 504 clinical isolates were collected in 2012,of which gram negative bacilli and gram positive cocci accounted for 76.2%, 23.8%,respectively.The most common pathogen in gram-negative rod was E.coli,K.pneumoniae,P.aeruginosa, A.baumanii and E.cloacae respectively.The most common pathogen in gram-positive cocci was S.aureus,E.facium,E-.faecalis,S.pneumoniae and S.epidermidis.ESBL rate of E.coli and K.pneumoniae was 66.5 and 46.7%.The resistant rate of E.coli,K.pneumoniae,E.cloacae to imipenem was 0.1%,0.5%,8.9% and to meropenem was 0.1%,0.6%,4.2%, respectively.P.aeruginosa was resistant to imipenem and meropenem were 38.9% and 32.3%.A.baumanii was resistant to imipenem and meropenem were 5 6.5% and 5 9.7%.Methicillin-resistant strains accounted for an average of 5 7.5% in S.aureus and 87.3% in coagulase negative staphylococcus.Staphylococcus was still susceptible to minocycline and chloram-phenicol.No staphylococcal strains were found resistant to vancomycin,linezolid.But a few coagulase negative staphylococcal strains were resistant to teicoplanin.Conclusion Surveillance of antimicrobial agents played an important role in controlling hospital infection.关键词
耐药监测/病原菌/药敏试验Key words
surveillance/pathogen/bacterial susceptibility testing分类
医药卫生引用本文复制引用
时东彦,赵文申,陈玉兰,郭映辉,冯军花,张征,田卫,徐晖,李书君,谢爽,刘金禄,赵建宏,李继红,曹丽军,董爱英,孙艳,王迁,刘建伟,张敏..2012年河北地区临床分离细菌分布及耐药性监测[J].现代检验医学杂志,2014,(5):49-53,57,6.