现代检验医学杂志Issue(1)：118-120,3.DOI:10.3969/j.issn.1671-7414.2015.01.034
黏质沙雷菌的耐药率分析及碳青霉烯酶的检测
Detection of Drug Resistance of Serratia Marcescens Rate Analysis and Carbapenemase
摘要
Abstract
Objective To analyze the drug resistance in clinical isolates of Serratiamarcescens of conventional treatment and carbapenemases,guiding the clinical rational drug use.Methods 106 strains of Serratiamarcescens from 2009~2012 year the clinical isolation,K-B disk diffusion susceptibility test,the modified Hodge method for screening the carbapenemase, Whonet statistical analysis.Results Serratia marcescens in sputum,secretions,swallow swab,urine samples were isolated 89 strains (84.1%),4 strains (3.8%),3 strains (2.8%)and 3 strains (2.8%).Serratiamarcescens resistant to ampicillin and cefazolin rate more than 90%,to aztreonam,cefepime,ceftazidime,piperacillin/tazobactam and Cefoperazone/sulbactam, drug resistance rate was 10%~22%,to amikacin,ciprofloxacin and imipenem were lower than 10%.Imipenem the resistant strains in 4 strains,the modified Hodge test positive 3 strains,the positive rate was 2.8%.Conclusion Serratiamarcescens extensively drug-resistant strains,the resistant mechanism is very complex,the institute has appeared carbapenemase produ-cing strains,clinicians should be based on the drug sensitivity test results.关键词
黏质沙雷菌/耐药率/碳青霉烯酶Key words
serratiamarcescens/resistance rate/carbapenemase分类
医药卫生引用本文复制引用
王欣,任超杰,扈会整,郝晓柯..黏质沙雷菌的耐药率分析及碳青霉烯酶的检测[J].现代检验医学杂志,2015,(1):118-120,3.基金项目
陕西省科学技术研究发展计划项目（项目编号2014K11-02-03-09）。 （）
