现代检验医学杂志Issue(2)：33-35,3.DOI:10.3969/j.issn.1671-7414.2015.02.010
尿毒症患者血液透析前后血清蛋白电泳图谱分析
Analysis of Serum Protein Electrophoresis Pattern in Uremic Patients Before and After Hemodialysis
摘要
Abstract
Objective To study the influence of hemodialysis on inflammatory state and immune function by analyzing the change of serum protein components in uremic patients before and after hemodialysis.Methods 75 cases of uremic patients confirmed by the Nephrology from October 2013 to May 2014 were selected as the observation group,and 15 healthy volun-teers at the same time as the control group.Then the serum protein electrophoresis pattern of observation group beford the first hemodialysis,after the first hemodialysis,after one month’s treatment and control group were compared with each oth-er.Results In the observation group before and after the first hemodialysis,the ALB levels were lower,α1 and α2 globulin levels were higher than those in control group.There was a statistically significant between the observation group before and after the first hemodialysis and control group (P <0.001).After the first hemodialysis,there were differences inα1 globulin levels compared with before the first hemodialysis (P <0.01).ALB was no significant difference after one month’s hemodi-alysis compared with before the first hemodialysis,andα1,α2 globulin were significantly reduced and the difference was sta-tistically significant (P <0.001),ALB was lower than the control group and was statistically significant (P <0.001).After one month’s hemodialysis,the levels ofγglobulin were higher than those in control group,before the first hemodialysis and after the first hemodialysis.There were significant differences (P <0.001 or P <0.01).Conclusion Regular and effective hemodialysis can improve inflammatory state and immune function of uremic patients.关键词
尿毒症/血液透析/血清蛋白电泳/免疫功能Key words
uremia/hemodialysis/serum protein electrophoresis/immune function分类
医药卫生引用本文复制引用
龚英峰,李顺利,杜勇,张贵松,杜金娥,张伟,冯绍明,裴荣光..尿毒症患者血液透析前后血清蛋白电泳图谱分析[J].现代检验医学杂志,2015,(2):33-35,3.基金项目
河北省医学科学研究重点课题计划项目（编号ZD20140069）。 （）
