现代检验医学杂志Issue(2)：87-90,4.DOI:10.3969/j.issn.1671-7414.2015.02.027
2527株临床分离病原菌的耐药性分析
Drug Resistance Spectrum Analysis of 2 527 Clinical Isolates of Bacteria
摘要
Abstract
Objective To investigate the resistance of clinical isolates from Yuebei People’s Hospital so as to provide the ref-erence for clinical use of antibiotics.Methods To comprehensively analyze the drug resistance,AST was performed with K-B or MIC method to 2 527 strains of clinical isolates and the data were analyzed by WHONET 5.4 and SPSS19.0 softwares according to the breakpoints of CLSI 2012 standard.Results MRSA accounted for 30.9% in Staphylococcus aureus iso-lates,MRCNS accounted for 76.2% incoagulase negative Staphylococcus isolates ,no detection of vancomycin or linezolid re-sistant strains.The antimicrobial drug resistance of Enterococcus faecium was significantly higher than that of Enterococcus faecalis ,no detection of glycopeptide and linezolid resistant strains in Enterococcus faecalis ,but one linezolid resistant strains and two teicoplanin resistant strains in Enterococcus faecalis .Enterobacteriaceae remain highly sensitive to carbapen-em antibiotics,ESBLs produced strains in Escherichia coli ,Klebsiella pneumoniae were 43.9% and 37.5% respectively,five polymyxin B resistant strains were detected in Pseudomonas aeruginosa ,and 63.7% of MDRO rate in Acinetobacter bau-mannii .Conclusion Drug resistance of clinical pathogenic bacteria remain seriously in hospital,clinical application of antibi-otics should be reasonable based on the result of drug sensitivity.关键词
病原菌/耐药性/药敏试验Key words
pathogenic bacteria/drug resistance/antibiotic susceptibility test分类
医药卫生引用本文复制引用
张河林,赵飞俊,何凤屏,罗君,黄晓云,尹卫国..2527株临床分离病原菌的耐药性分析[J].现代检验医学杂志,2015,(2):87-90,4.基金项目
湖南省自然科学基金重点项目（项目编号12JJ2045）资助。 （）
