现代检验医学杂志Issue(2):94-96,3.DOI:10.3969/j.issn.1671-7414.2015.02.029
两种试剂检测抗心磷脂抗体的比较
Comparison of Two Kits in Determining Anti-Cardiolipin
摘要
Abstract
Objective To compare the results of anti-cardiolipin (ACA)measuring by two commercial available kits.Methods ACA in total of 66 serum samples were both determined by kits from Euroimmun and YHLO simultaneously,then the re-sults were analyzed comparatively and correlatively.The Euroimmun kit was applied to determination the level of ACA-IgA/G/M,and the YHLO kit determined ACA-IgG/M and anti-β2-glycoprotein I antibody (β2GPI IgG).Results The positive rate by Euroimmun kit was 37.88% (25/66),while 31.82% (21/66)was positive (one positive among ACA-IgG,IgM andβ2GPI IgG)when determined by YHLO kit,and there was no significant difference between the two kits.The accordance rate of the two kits was 87.88% (58/66).The ACA-IgA/G/M value by Euroimmun kit and the summation of ACA-IgG, IgM andβ2GPI IgG by YHLO kit showed well linear correlation (r 2 =0.892,P <0.01).Conclusion Results from the two kits were consistent and correlated well,and they are suitable for the clinical application;these two kits have their own char-acteristics,which could be used by individual or combination accordingly.关键词
抗心磷脂抗体/抗β2糖蛋白I抗体/相关性Key words
anti-cardiolipin/anti-β2-glycoprotein I antibody/association分类
医药卫生引用本文复制引用
朱益佳,徐龙珍,胡伟,陶月,张葵,王庆飞..两种试剂检测抗心磷脂抗体的比较[J].现代检验医学杂志,2015,(2):94-96,3.基金项目
南京市医学科技发展专项资金(YKK13066)。 ()