陕西医学杂志Issue(9)：1107-1109,3.DOI:10.3969/j.issn.1000-7377.2014.09.001
小儿血液系统疾病人细小病毒B 19感染的研究
The investigation of HPV B19 infection on children with blood system diseases
摘要
Abstract
Objective:To investigate the relationship between human parvovirus B 19 (HPV B19 ) infection and children who had blood system disease .Methods :PCR and ELISA methods were used to detecte HPV B19-DNA and HPV B19-IgG in child who had idiopathic thrombocytopenic purpura ,aplastic anemia or leukemia .Results :The positive rate of HPV B19-IgG was 43 .08% in patient with idiopathic thrombocytopenic purpura ,the positive rate of HPV B19-IgG was 41 .07% in patient with leukemia ,and the positive rate of HPV B19-IgG was 21 .43% in patient with aplastic anemia .There were statistical differences between the experiment groups and the control group .The positive rate of HPV B19-DNA was 40 .00% in patient with idiopathic thrombocytopenic purpura ,the positive rate of HPV B19-DNA was 27 .68% in patient with leukemia ,and the positive rate of HPV B19-DNA was 21 .43% in patient with aplastic anemia .Conclusion :HPV B19 infection have relationship with some children who have blood system dis-eases in northwest region of China .关键词
紫癜 ,血小板减少性 ,特发性/并发症/贫血 ,再生障碍性/病因学/白血病/病因学/人细小病毒B19Key words
Purpura thrombocytopenic idiopathic/complications/Anemia aplastic/etiology/Leuke-mia/etiology/Human parvovirus B19分类
医药卫生引用本文复制引用
许东亮,张国成,聂晓晶,孙新,吴海霞,徐晓莉..小儿血液系统疾病人细小病毒B 19感染的研究[J].陕西医学杂志,2014,(9):1107-1109,3.基金项目
国家自然科学基金（81070543）；南京军区医学科技创新课题 （）
