陕西医学杂志Issue(10)：1362-1364,3.DOI:10.3969/j.issn.1000-7377.2014.10.045
首剂阿托伐他汀强化负荷对正常低密度脂蛋白心梗患者急诊PCI中无复流的作用
The effects of first intensive dose atorvastatin on no-reflow in acute myocardial infarction patients of normal LDL-C treated with percutaneous coronary intervention
摘要
Abstract
Objective:To observe the the effects of first dose 80 mg atorvastatin on no-reflow in ST-seg-ment elevation acute myocardial infarction patients of normal LDL-C treated with percutaneous coronary interven-tion .Methods:80 patients of normal LDL-C with STEAMI successfully treated with PCI were divided into the treat-ment group(40 patients )and the control group (40 patients ) .The treatment patients were given preoperative dose of atorvastatin 80 mg before the PCI ,40 mg daily after one day for 2 weeks ,20mg daily for long-term .The control pa-tients were given atorvastatin 40 mg before the PCI ,40 mg daily for 2 weeks ,20 mg daily for long-term .The inci-dence of no-reflow was observed .Results :There were no significant adverse reactions in the two groups .The treat-ment group of no-reflow incidence was 10% ,the control group of no-reflow was 22 .5% .The difference was statisti-cally significant (P<0 .05) .Conclusion :First given 80 mg atorvastatin before PCI can reduce the incidence of no-re-flow with acute STEMI of normal LDL-C .关键词
心肌梗塞/经皮冠状动脉介入治疗/脂蛋白类/LDL西司他汀类/心肌再灌注Key words
Myocardial infarction/Percutaneous coronary/Intervention Lipoproteins/LDL Cystatins/Myocardial reperfusion分类
医药卫生引用本文复制引用
付文波,丁世芳,陈志楠,蒋桔泉,龚志刚,李志刚,卢青..首剂阿托伐他汀强化负荷对正常低密度脂蛋白心梗患者急诊PCI中无复流的作用[J].陕西医学杂志,2014,(10):1362-1364,3.基金项目
湖北省卫生厅青年人才基金项目 （）
