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肾小球滤过率在2型糖尿病患者肾功能评估中的应用价值

董春萍 乔媛 崔波 董莉 吴贵福 王养维

陕西医学杂志Issue(10):1369-1371,3.
陕西医学杂志Issue(10):1369-1371,3.DOI:10.3969/j.issn.1000-7377.2014.10.048

肾小球滤过率在2型糖尿病患者肾功能评估中的应用价值

The clinical application of glomerular filtration rate in patients type 2 diabetes

董春萍 1乔媛 1崔波 1董莉 1吴贵福 1王养维1

作者信息

  • 1. 陕西省人民医院 西安710068
  • 折叠

摘要

Abstract

Objective :To analyze the changes of glomerular filtration rate (GFR) and its influencing fac-tors in type 2 diabetic patients .Methods :A total of 216 type 2 diabetic patients were studied .Body mass index , blood pressure ,HbA1c ,Scr ,BUN ,uric acid ,profile of plasma lipid and UACR were measured ;GFR determina-tion was performed by99m Tc-DTPA .Results :The proportion of patients with GFR≥60mL/(min · 1 .73m2 ) was 86 . 6% ,patients with GFR<60mL/(min · 1 .73m2 ) was 13 .4% .Between two groups ,there were significant differ-ences in age ,diabetes mellitus duration ,SBP ,BUN ,SCr ,Cys ,UACR .Normoalbuminuria was found in 126 pa-tients ,microalbuminuria was found in 52 patients ,and macroalbuminuria was found in 38 patients .In three groups , the proportion of patients with GFR<60mL/(min · 1 .73m2 ) were 6 .3% 、11 .5% 、39 .5% .Logistic regression anal-ysis showed age、UACR were the main influencing factors of GFR in patients with type 2 diabetes .Conclusion :The renal function of the patients with type 2 diabetes will be exactly judged by combining measurement of both GFR and UACR .

关键词

糖尿病/2型/肾小球滤过率/白蛋白尿/尿微量白蛋白肌酐比值

Key words

Diabetes mellitus/type 2/Glomerular filtration rate/Albuminuria/UACR

分类

医药卫生

引用本文复制引用

董春萍,乔媛,崔波,董莉,吴贵福,王养维..肾小球滤过率在2型糖尿病患者肾功能评估中的应用价值[J].陕西医学杂志,2014,(10):1369-1371,3.

基金项目

陕西省科学技术研究发展计划项目 ()

陕西医学杂志

OACSTPCD

1000-7377

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