陕西医学杂志Issue(6)：735-737,3.DOI:10.3969/j.issn.1000-7377.2015.06.043
羟考酮在剖宫产术后静脉自控镇痛中的应用
The use of the postoperative analgesia effects of oxycodone in cesarean section patients
摘要
Abstract
Objective:To evaluate the postoperative analgesia effects of oxycodone in cesarean section pa‐tients .Methods :Sixty ASA I or II patients undergoing elective caesarean section were randomly divided into 2 groups (n= 30 each):sufentanil with ketorolac tromethamine group (ST group) and oxycodone with ketorolac tromethamine group (QT group) .All of the patients received spinal anesthesia and patient‐controlled intravenous analgesia (PCIA) after operation .PCIA solution contained sufentanil (1μg/kg) ,ketorolac tromethamine (1 .5mg/kg) and tropisetron(10mg) in 100 ml of normal saline in ST group .Differently ,PCIA solution contained oxycodone (1mg/kg)、ketorolac tromethamine (1 .5mg/kg) and tropisetron(10mg) in 100 ml of normal saline in OT group . The VAS and BCS scores at 4 ,6 ,12 ,24 and 48 hours after operation were recorded respectively .Side effects of post‐operative analgesia ,press number of times and the use of analgesic except PCIA within 48 hours were also collected . Results:Compared with ST group ,VAS scores and press number of times at 4 ,6 ,12 ,and 24 hours in OT group af‐ter operation were reduced (P<0 .05) .BCS scores at 4 ,6 ,12 ,and 24 hours in OT group after operation were in‐creased (P<0 .05) .The incidence of nausea and vomiting after operation in OT group was reduced compared with that in the ST group (P<0 .05) .There were three people have used analgesic except PCIA in ST group but no one in QT group .Conclusion:Oxycodone with ketorolac tromethamine in PCIA showed an improved postoperative analge‐sia in caesarean section patients without increasing side effects .关键词
剖宫产术/镇痛 ,病人控制/舒芬太尼/酮咯酸氨丁三醇/镇痛药 ,阿片类Key words
Cesarean section/Analgesia ,patient-controlled/Sufentanil/Ketorolac tromethamine/Analgesics ,opioid分类
医药卫生引用本文复制引用
熊虹飞,李思远,刘鸿涛,雷丹,刘圆,吴刚..羟考酮在剖宫产术后静脉自控镇痛中的应用[J].陕西医学杂志,2015,(6):735-737,3.基金项目
国家自然科学基金资助项目（31300675）高等学校博士学科点专项科研基金资助项目 （）
