陕西医学杂志Issue(7):806-809,4.DOI:10.3969/j.issn.1000-7377.2015.07.012
肺炎支原体肺炎患儿血清及支气管肺泡灌洗液中SP-A、SP-D和KL-6含量变化及意义
Alterations of SP-A,SP-D and KL-6 in serum and bronchoalveolar lavage fluid in children with Mycoplasma pneumoniae pneumonia
摘要
Abstract
Objective:To study the alterations and relationship of surfactant protein(SP)‐A ,SP‐D and KL‐6 in serum and bronchoalveolar lavage fluids (BALF) in children with Mycoplasma pneumonia pneumonia (MPP) .Methods:Self‐control method was used for the study on SP‐A ,SP‐D and KL‐6 in serum ,infected and non‐infected BALFs in 32 MMP children with only one side of MPP .Results :The contents of SP‐A ,SP‐D and KL‐6 in infected BALF were 243(90‐468) ,187(43‐333) ,148(47‐426);104(37‐257) ,56(25‐131) ,35(12‐147) in non‐infec‐ted BALF;35(25‐69) ,33(9‐149) and 24(15‐62) in serum .The correlation coefficient of KL‐6 between serum and infected BALF were‐0 .534 and‐0 .378 .Conclusion:There are significant correlation between the alterations of SP‐A ,SP‐D and KL‐6 in serum and lung infection in children with CAP .KL‐6 in serum may be more sensitive than SP‐A and SP‐D .关键词
肺炎,支原体/病理生理学/肺表面活性蛋白/支气管肺泡灌洗液/儿童Key words
Pneumonia mycoplasma/physiopathology/Pulmonary surfactant protein/Bronchoalveolar lavage fluid/Child分类
医药卫生引用本文复制引用
柴玲彦,赵红,刘连凤,刘彦霞,杨秀丽..肺炎支原体肺炎患儿血清及支气管肺泡灌洗液中SP-A、SP-D和KL-6含量变化及意义[J].陕西医学杂志,2015,(7):806-809,4.基金项目
石家庄市科学技术研究与发展指导计划课题 ()