实用肝脏病杂志Issue(1)：38-42,5.DOI:10.3969/j.issn.1672-5069.2015.01.010
非酒精性脂肪性肝病痰瘀证与颈动脉内膜中层厚度的关系探讨
Application of intima-media thickness of carotid artery in diagnosis of phlegm-stasis syndrome in pa-tients with nonalcoholic fatty liver diseases
摘要
Abstract
Objective To investigate the application of intima-media thickness (IMT) of carotid artery in diagnosis of phlegm-stasis syndrome in patients with nonalcoholic fatty liver diseases (NAFLD). Methods The patients with nonalcoholic fatty liver diseases were diagnosed and the intima-media thickness of carotid artery was detected by sonography. Results Out of 80 patients with NAFLD,there were 30 with Phlegm syndrome,30 with Stasis syndrome and 20 with indistinguishable syndrome based on the syndrome determination criteria of Chinese traditional medicine. The moderate to severe degree of fatty liver accounted for 88.9% and the patients with Phlegm syndrome for 83.3% in 54 patients with increased IMT of carotid artery;the waist circumference,basic mass index (BMI),fasting blood glucose (FBG),HOMA-IR and cholesterol increase significantly as compare to those in healthy persons(P<0.01);IMT in patients with NAFLD were (1.19 ±0.75)mm,significantly higher than in control(0.71±0.25)mm(P<0.01);Logistic regression analysis showed that the FBG(OR:5.48,95%CI:1.39~21.61), total cholesterol (OR:1.14,95%CI:1.14~12.82),BMI(OR:1.20,95%CI:1.02~1.42),age(OR:1.02,95%CI:1.01~1.03) and Phlegm syndrome (OR:1.10,95%CI:1.03~1.17) were the independent risk factors for increase IMT in patients with NAFLD. Conclusions The IMT of carotid artery is closely related to the Phlegm syndrome and fat-ty liver degree in patients NAFLD,so it might be used as a parameter for determination of phlegm-stasis syn-drome by Chinese traditional medicine.关键词
非酒精性脂肪性肝病/颈动脉内膜中层厚度/中医辨证分型Key words
Nonalcoholic fatty liver diseases/Intima-media thickness of carotid artery/Syndrome differenti-ation of TCM引用本文复制引用
胡晨波,李仲平,潘洁萍,季平,严蓉妹,沈美蓉,张金香,潘云鹤..非酒精性脂肪性肝病痰瘀证与颈动脉内膜中层厚度的关系探讨[J].实用肝脏病杂志,2015,(1):38-42,5.基金项目
国家中医药管理局中医药防治传染病临床基地建设项目 （）
