实用肝脏病杂志2015，Vol.18Issue(3)：262-265,4.DOI:10.3969/j.issn.1672-5069.2015.02.011
复方牛胎肝提取物治疗乙型肝炎肝硬化疗效观察
Efficacy of compound embryonic bovine liver extract in patients with hepatitis B related liver cirrhosis
卢敏 1毛华 1黄纯炽 1唐银丽 1张能友 2席建东3
作者信息
- 1. 510282 广州市 南方医科大学珠江医院消化内科
- 2. 北京解放军 93682 部队门诊部
- 3. 珠江医院放射科
- 折叠
摘要
Abstract
Objective To investigate the effect of compound embryonic bovine liver extract in patients with hepatitis B related liver cirrhosis. Methods One hundred and twenty patients with hepatitis B induced liver cir-rhosis were randomly divided into two groups,with 80 in treatment group receiving compound embryonic bovine liv-er extract tablets at the base of basic liver-protecting treatment and 40 in control group receiving the basic liv-er-protecting treatment only for 3 months. Liver function tests,liver stiffness measurement (LSM) by Fibrotouch,and portal vein diameters,spleen thickness and splenic vein width before and after treatment were compared in both groups. Results At the end of 3-month treatment,serum TBIL,ALT,and LSM values in patients in treatment group were (33.0±2.07)μmol/L,(36.40±5.86) U/L,(10.78±1.15) Kpa,respectively,significantly decreased as compared with those in the controls [(48.62±4.24)μmol/L,(52.60±7.3) U/L,(15.26±2.17) Kpa,respectively, P<0.05 for all];serum ALB levels in patients in treatment group increased significantly compared with that in con-trols[(35.0±1.58) g/L vs. (31±1.58) g/L,P<0.05];portal vein diameters,spleen thickness and splenic vein widths remarkably decreased compared with those in patients in the control group [(1.26±0.08) cm vs. (1.36±0.05) cm,(3.97±0.04) cm vs. (4.20±0.10) cm,(0.87±0.02) cm vs. (0.92±0.02) cm,P<0.05 for all]. Conclusions Compound embryonic bovine liver extract can significantly improve the liver function and inhibit liver fibrosis in patients with hepatitis B induced liver cirrhosis.关键词
肝硬化/乙型肝炎/复方牛胎肝提取物/疗效Key words
Liver cirrhosis/Compound embryonic bovine liver extract/Hepatitis B/Efficacy引用本文复制引用
卢敏,毛华,黄纯炽,唐银丽,张能友,席建东..复方牛胎肝提取物治疗乙型肝炎肝硬化疗效观察[J].实用肝脏病杂志,2015,18(3):262-265,4.
