实用医学杂志Issue(7)：1016-1020,5.DOI:10.3969/j.issn.1006-5725.2014.07.003
缺血性卒中后非流利型失语患者静息态功能磁共振比率低波振幅的研究
Resting-state fMRI fALFF analysis in patients with non-fluent aphasia after ischemic stroke
摘要
Abstract
Objective To understand the impairment and compensation mechanism of brain function in pa-tients with non-fluent aphasia after ischemic stroke. The fractional amplitude of low frequency fluctuation (fALFF) method was used to analyze the functional magnetic resonance imaging (fMRI) data in the resting state between the aphasia patients and the normal controls. Methods The scans of the resting state of fMRI were performed in 17 aphasia patients and 19 age-, education-, and sex-matched healthy control subjects. The scan sequence was single-shot echo planar image,DPARSF software was used to analyze fALFF data of the aphasia patients and the healthy controls. Results Compared to the control group, the value in right superior temporal gurus, inferior parietal lob-ule, frontal lobe cortex, and postcentral gurus were significantly increased in the aphasia group. The fALFF in bilat-eral cerebellum and right thalamus were also decreased in the aphasia group. Conclusions The fALFF values in some brain region in the aphasia group were abnormal in the resting state , indicating a few pathological change of brain function in patients with non-fluent aphasia after ischemic stroke.关键词
卒中/缺血性卒中后非流利型失语/功能磁共振成像/比率低频振幅Key words
Stroke/Non-fluent aphasia after ischemic stroke/Functional magnetic resonance imaging/Fractional amplitude of low frequency fluctuation引用本文复制引用
许光,马晓芬,江桂华,李淑美,田军章,詹文峰,方金,邱迎伟..缺血性卒中后非流利型失语患者静息态功能磁共振比率低波振幅的研究[J].实用医学杂志,2014,(7):1016-1020,5.基金项目
广东省自然科学基金立项项目 （）
