实用医学杂志Issue(12)：1883-1886,4.DOI:10.3969/j.issn.1006-5725.2014.12.009
牙槽嵴位点保存的动物实验研究
An experimental study of alveolar ridge preservation after tooth extraction in dog
摘要
Abstract
Objective To histomorphometricly assess changes occurred in the alveolar ridge following different methods of socket preservation and to compare them against natural healing without interventions. Methods The second、 third and fourth mandibular premolars were extracted from six beagles. Six extraction sites in each dog were randomly assigned to three treatments as follows:natural healing (T1), Bio-Oss Collagen (T2) and immediate implant with Bio-Oss (T3). Six month after surgery, the dogs were euthanized and tissue samples were sectioned, fixed and mounted, then were stained with toluidine blue. The histologic studies and morphological measurements were performed by using an optical microscope and a digital image software. Results Reabsorption in the buccal aspect of the alveolar crest of ridge was showed in all groups. With respect to the mean vertical bone loss of the buccal bone plate, T3 is lower than T1 and T2(P<0.001 ), while no significant differences were observed between T1 and T2. With regard to horizontal dimension of the alveolar process , a statistical significance could be found at 3mm and 4mm below the crest of ridge in group T1 and T3(P=0.017, P=0.042), while no statistical differences were found between other groups. Conclusions Both techniques of alveolar ridge preservation were not able to completely preserve the original bone volume after tooth extraction. Immediate implant placement in combination with Bio-Oss seems to have the potential to limit the reabsorption of the alveolar process efficiently , but the bone preserving effect of Bio-Oss Collagen is undesirable.关键词
牙槽嵴位点保存/Bio-Oss Collagen/即刻种植/骨吸收Key words
Alveolar ridge preservation/Bio-Oss Collagen/Immediate implant/Bone resorption引用本文复制引用
连珊,卿玲,谢宇,罗震,黄建生..牙槽嵴位点保存的动物实验研究[J].实用医学杂志,2014,(12):1883-1886,4.基金项目
广东省科技计划重点引导项目（编号2010B03160011）；广东省医学科学技术研究基金 （）
