实用医学杂志Issue(16)：2658-2662,5.DOI:10.3969/j.issn.1006-5725.2014.16.044
中成药辨证论治慢性肾脏病3-4期的多中心前瞻性临床研究
Prospective multicenter study on syndrome differentiation-based treatment with traditional Chinese medicine for Chronic Kidney Disease (CKD3-4)
摘要
Abstract
Objective To study the clinical curative effect of syndrome differentiation-based treatment with traditional Chinese medicine on patient with Chronic Kidney Disease (CKD3-4). Method According to prospective multicenter randomized controlled study which was applied to the patients with CKD3-4 , the total of 339 patients were divided into two groups. To one group as standard including 167 patients ,the other including 172 patients. Chinese Traditional Patent Medicine single or combined-prescription oral treatment according to syndrome differentiation-based treatment was employed. To the other group as reference , Chinese Traditional Patent Medicine oral treatment according to experienced rule was applied. The clinical curative effect results were obtained after a 24 weeks-treatment. Result The Scr ,eGFR and UTP with CKD3 in standard group illustrate statistics significance (P<0.05). On the opposite, those of the reference group remain insignificance (P > 0.05). The clinical curative effect result of patient in standard group was better than that of reference group. About the clinical curative effect of CKD4, no statistics significance difference (P > 0.05) could be found between groups or between patients in one group. The TCM score of patient with CKD3-4 in standard group have improved (P < 0.05) according to baseline. However, that of reference group did not show any statistics significance (P > 0.05). Conclusion Syndrome differentiation-based treatment with traditional Chinese medicine illustrated a better result in protection of renal function, reduction in urinary protein and decline in TCM score than the treatment according to experienced rule.关键词
慢性肾脏病/3-4期/中成药/辨证论治Key words
Chronic Kidney Disease (CKD3-4)/Chinese Traditional Patent Medicine/Syndrome differentiation-based treatment引用本文复制引用
孟元,杨彦芳,刘洋,任建伟,程虹,刘建平,张胜容,刘宝利,李靖,赵轶雯,王雨,赵静,赵文景,葛楠..中成药辨证论治慢性肾脏病3-4期的多中心前瞻性临床研究[J].实用医学杂志,2014,(16):2658-2662,5.基金项目
首都医学科技发展基金资助课题 （）
