实用医学杂志Issue(19)：3166-3169,4.DOI:10.3969/j.issn.1006-5725.2014.19.047
香港海鸥型菌对喹诺酮耐药性的检测分析
Analysis on testing of quinolone resistance in Laribacter Hongkongensis
摘要
Abstract
Objectives To investigate the prevalance of quinolone resistance in Laribacter hongkongensis and to evaluate the influence of agar dilution and disc diffusion methods on susceptibility testing for the bacterium. Methods Susceptibility to quinolones of L.hongkongensis was tested by agar dilution and disc diffusion methods. The results for both methods were compared. Results L.hongkongensis isolates exhibited different susceptibility rate for quinolones (levofloxacin>ciprofloxacin>norfloxacin>nalidixic acid). All of the fish isolates were susceptible to levofloxacin and more than 90%were susceptible to ciprofloxacin and Norfloxacin. However,by agar dilution, only 62.50%, 37.50%,48.21%, 19.64%of the frogs isolates were susceptible to levofloxacin, norfloxacin, ciprofloxacin, nalidixic acid, respectively. For fish isolates, comparision of susceptibilities between agar dilution and disc diffusion showed a high (> 95%) percentage agreement for levofloxacin and ciprofloxacin and the highest crepancies were observed with norfloxacin (100%) .But it showed a high discrepancy when comparing the two methods for frogs isolates. Conclusions The resistance rate of L. hongkongens to quinolones was high , especially for frog isolates. The results suggested the use of agar dilution on susceptibility testing for quinolones in L. hongkongensis.关键词
香港海鸥型菌/喹诺酮类药物/敏感性Key words
Laribacter hongkongensis/Quinolones/Drug susceptibility引用本文复制引用
朱丽东,肖锋,杨羚,陈定强..香港海鸥型菌对喹诺酮耐药性的检测分析[J].实用医学杂志,2014,(19):3166-3169,4.基金项目
国家自然科学基金项目 （）
