实用医学杂志Issue(20)：3324-3326,3.DOI:10.3969/j.issn.1006-5725.2014.20.043
喷他佐辛在健忘镇痛慢诱导麻醉中对气管插管应激反应的影响
Effects of pentazocine on intubation stress response during slow induction of anesthesia
摘要
Abstract
Objective To investigate the effect of pentazocine combined with midazolam on intubation stress response in slow induction of anesthesia. Mtheods Forty ASAⅠ~Ⅱpatients were divided into two groups. Anesthesia was induced with midazolam 0.03 mg/kg in both groups,and pentazocine 0.8 mg/kg (i.v.) was given in pentazocine group or fentanyl 2 μg/kg (i.v.) in fentanyl group. Five minutes later, 2 mL of 1% decicaine was administered by cricothyroid membrane puncture to facilitate the intubation.The SpO2, circulatory indexes (HR, SBP, DBP, BIS) and sedation level were measured at T0, T1, T2, T3, T4, T5, T6. Results Both pentazocine and fentanyl can inhibit stress responses to tracheal intubation effectively,but pentazocine group is better than fentanyl group on the cardiovascular stability during slow induction of anesthesia. Conclusion Pentazocine 0.8 mg/kg can inhibit stress responses to tracheal intubation effectively with a low incidence of adverse reactions in the slow induction of anesthesia.关键词
喷他佐辛/芬太尼/健忘镇痛慢诱导麻醉/应激反应Key words
Pentazocine/Fentanyl/Slow induction of anesthesia/Stress Response引用本文复制引用
李国利,王暐,刘薇,滕金亮,李福龙..喷他佐辛在健忘镇痛慢诱导麻醉中对气管插管应激反应的影响[J].实用医学杂志,2014,(20):3324-3326,3.基金项目
河北省张家口市2013年度科学技术研究与发展计划项目（编号1321096D）；河北省张家口市2010年科学技术研究与发展指令计划项目 （）
