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初筛Rh(D)阴性无缘献血者弱D和Del表型调查

张松 常利 宋任浩

实用医学杂志Issue(24):4028-4030,3.
实用医学杂志Issue(24):4028-4030,3.DOI:10.3969/j.issn.1006-5725.2014.24.055

初筛Rh(D)阴性无缘献血者弱D和Del表型调查

Investigation on the distribution of weak D and Del phenotype in unrelated blood donors with negative Rh(D)

张松 1常利 2宋任浩3

作者信息

  • 1. 050051 石家庄市,河北医科大学第三医院检验科
  • 2. 050051 石家庄市,河北医科大学第三医院康复科
  • 3. 130100 河北省血液中心
  • 折叠

摘要

Abstract

Objective To investigate the distribution of weak D and Del phenotype in unrelated blood donors with negative Rh (D). Methods Four hundred and nineRhD (-) unrelated donors were screened by the saline agglutination method. Type weak D was detected by the indirect antiglobulin test, and type Del was detected by absorb radiation method. Results In 409 RhD (-) samples, 27 cases (6.61%) of type weak D were checked out, and 61 cases (14.91%) were type Del and 321 cases (78.48%) were corroborate for RhD (-), In the confirmed RhD (-) blood donors, phenotype ccee was most (49.14%), followed by Ccee (23.47%), People with phenotype ccEe accounted for 4.16%in type weak D, followed by Ccee (1.71%). Ccee accounted for 10.02%in type Del, and Ccee accounted for 1.71%. Conclusion RhD (-) donors screened by regular testing should adopt a more sensitive test for verifing type weak D or Del. In order to ensure the security of blood transfusion, people with type weak D and Del should be regarded as RhD positive blood donors, and the RhD negative people deemed to be recipients.

关键词

初筛/Rh(D)阴性/弱D表型/Del表型

Key words

Preliminary screening/RhD (-) blood group/Weak D phenotype/Del phenotype

引用本文复制引用

张松,常利,宋任浩..初筛Rh(D)阴性无缘献血者弱D和Del表型调查[J].实用医学杂志,2014,(24):4028-4030,3.

基金项目

河北省医学科学研究重点课题计划 ()

实用医学杂志

OA北大核心CSTPCD

1006-5725

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