实用医学杂志Issue(5)：740-742,3.DOI:10.3969/j.issn.1006-5725.2015.05.015
丝氨酸／苏氨酸激酶15在甲状腺乳头状癌诊治中的意义
Expression and significance of STK15 gene in parpillary thyroid carcinoma
摘要
Abstract
Objective To explore the expression of serine/threonine kinase 15 (STK15) gene and its significance for papillary thyroid carcinoma. Methods SP immunohistochemical method was used to detect the expression of STK15 gene in 71 cases of papillary thyroid carcinoma and 45 cases nodular goiter tissue. Results The positive expression rates of STK15 gene in 71 cases of papillary thyroid carcinoma were 100%, and the adjacent of papillary thyroid carcinoma expressions of STK15 gene 8.5%, nodular goiter tissue of STK15 gene expression rates 24.4%. The expression of STK15 gene was positively correlated with that of STK15 gene in papillary thyroid carcinoma (P < 0.01). Conclusion High expression of STK15 gene is confirmed in papillary thyroid carcinoma. The detection of STK15 gene can provide valuable evidence for diagnosis of papillary thyroid carcinoma and evaluation of the malignant potential of nodular goiter.关键词
甲状腺肿瘤/丝氨酸/苏氨酸激酶15/诊断/治疗Key words
Papillary Thyroid Carcinoma/Serine/Threonine Kinase 15/Diagnosis/Treatment引用本文复制引用
孙淑明,杨秀珣,陈耿芝,卢晓峰,林豪雨,梁伟全,陈春发..丝氨酸／苏氨酸激酶15在甲状腺乳头状癌诊治中的意义[J].实用医学杂志,2015,(5):740-742,3.基金项目
汕头市科技局资助项目 （）
