实用医学杂志Issue(7)：1123-1125,3.DOI:10.3969/j.issn.1006-5725.2015.07.025
系统性红斑狼疮患者外周血维生素D水平及其临床意义
Serum vitamin D levels in patients with systemic lupus erythematosus and their relationship with disease activity
摘要
Abstract
Objective To detect the serum 25- OH-D levels in patients with systemic lupus erythematosus (SLE) and investigate the function of vitamin D in the pathogenesis of SLE. Methods Eighty SLE patients including 40 healthy donors and 40 RA (rheumatoid arthritis) patients were enrolled in this study. Serum 25-OH-D levels were detected with ECL method. Results (1)Serum 25-OH-D levels in patients with active SLE were lower than those with inactive SLE patients and healthy controls. (2)Serum 25-OH-D levels were negatively correlated with SLEDAI (Systemic Lupus Erythematosus Disease Activity Index) scores (r = -0.45,P < 0.01) and 24-hours urinary protein excretion (r = -0.32,P < 0.05). Conclusion Serum 25-OH-D levels in SLE patients decrease and have close relationship with disease activity and renal lesions.关键词
系统性红斑狼疮/25-OH-D/电化学发光法Key words
Systemic lupus erythematosus/25-OH-D/electrochemiluminescence引用本文复制引用
卢勤燕,蔡小燕,林小军,唐莼,叶静华,李伟念,何志翔,李欣颖,张荣伟..系统性红斑狼疮患者外周血维生素D水平及其临床意义[J].实用医学杂志,2015,(7):1123-1125,3.基金项目
广东省科技计划项目 （）
