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脂蛋白(a)与急性冠脉综合征患者冠脉左主干病变的相关性

尚东丽 刘建华

实用医学杂志Issue(7):1132-1134,3.
实用医学杂志Issue(7):1132-1134,3.DOI:10.3969/j.issn.1006-5725.2015.07.028

脂蛋白(a)与急性冠脉综合征患者冠脉左主干病变的相关性

Correlation between lipoprotein(a) and left main coronary artery disease in patients with acute coronary syndrome

尚东丽 1刘建华1

作者信息

  • 1. 473010 河南省南阳市第一人民医院心内科
  • 折叠

摘要

Abstract

Objectives To explore the correlation between lipoprotein (a) and left main coronary artery ( LMCA) disease in patients with acute coronary syndrome (ACS). Methods A total of 264 ACS patients managed with coronary angiography (CAG) from June 2012 to December 2013 were included in the study and then they were divided into 2 groups (high-Lp(a) (> or = 300 mg/L) group (n = 93) and low-Lp(a) (< 300 mg/L)group(n = 171). The clinical data were studied and compared between the two groups. Binary unconditional logistic regression analysis was used to select the risk factors of LMCA disease. Results The percentages of multiple branch lesion (43.0% vs. 25.1%) and LMCA disease (17.2% vs. 8.2%)were higher in the high-Lp(a) group as compared with the low-Lp(a) group (P<0.05). Logistic regression analysis showed Lp(a) was independent factor of LMCA disease. Conclusions In ACS patients the elevated Lp(a) levels are associated with the severity of coronary disease and Lp(a) is an independent factor of LMCA disease.

关键词

急性冠脉综合征/脂蛋白(a)/左主干病变/冠状动脉疾病

Key words

Acute coronary syndrome/Lipoprotein (a)/Left main coronary artery/Coronary artery disease

引用本文复制引用

尚东丽,刘建华..脂蛋白(a)与急性冠脉综合征患者冠脉左主干病变的相关性[J].实用医学杂志,2015,(7):1132-1134,3.

实用医学杂志

OA北大核心CSTPCD

1006-5725

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