实用医学杂志Issue(7)：1134-1136,3.DOI:10.3969/j.issn.1006-5725.2015.07.029
间断小剂量尿激酶治疗肺栓塞临床观察
Effect of intermittent use of low-dose urokinase on pulmonary embolism
雷蕾 1杨军兰 1解好群 1崔佳1
作者信息
- 1. 730000 兰州市，解放军第一医院呼吸内科
- 折叠
摘要
Abstract
Objective To evaluate the efficacy and safety of intermittent use of low-dose urokinase in the treatment of pulmonary embolism. Methods Forty-two patients with acute pulmonary embolism were divided into UK group with UK 10 000 U/(kg·d),7 days and rt-PA group with rt-PA 50 mg/2 h randomly. The efficacy was determined by the improvement of right heart dysfunction and perfusion defect 8 d and 14 d after the treatment. The bleeding incidence, death rate and PE recurrence were also evaluated. Results Differences of right heart dysfunction and perfusion defect between UK group and rt-PA group indicated no statistical significance (P >0.05).The rate of bleeding in UK group was lower than that of rt-PA group. Conclution The intermittent use of low-dose urokinase in the treatment of pulmonary embolism exhibits similar efficacy as rt-PA.关键词
肺栓塞/小剂量尿激酶/rt-PA/溶栓Key words
Pulmonary embolism/Low-dose urokinase/rt-PA/Thrombolysis引用本文复制引用
雷蕾,杨军兰,解好群,崔佳..间断小剂量尿激酶治疗肺栓塞临床观察[J].实用医学杂志,2015,(7):1134-1136,3.
