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随机尿白蛋白/肌酐比值对妊娠期高血压疾病的预测价值

阴红 高云飞 何淑明 余艳萍 黄启涛 王艳 孔紫靖 钟梅

实用医学杂志Issue(9):1441-1443,3.
实用医学杂志Issue(9):1441-1443,3.DOI:10.3969/j.issn.1006-5725.2015.09.017

随机尿白蛋白/肌酐比值对妊娠期高血压疾病的预测价值

Predictive value of random spot albuminuria to creatinine ratio in women with hypertensive disorders complicating pregnancy

阴红 1高云飞 2何淑明 1余艳萍 3黄启涛 3王艳 1孔紫靖 1钟梅3

作者信息

  • 1. 510515 广州市,南方医科大学南方医院妇产科
  • 2. 528415 广东省中山市,南方医科大学附属小榄医院妇产科
  • 3. 528415 广东省中山市,南方医科大学附属小榄医院妇产科
  • 折叠

摘要

Abstract

Objective To determine the random spot albuminuria to creatinine ratio (ACR) of normal pregnant women , to track the pregnancy outcome , and to discuss the predictive value of ACR in women with hy-pertensive disorders complicating pregnancy (HDCP). Methods Except for 87 pregnant women suffering from HDCP, 2 038 pregnant women were enrolled in this study. ACR, routine examinations of blood and urine, blood biochemical, 24-hr urinary protein were determined. Results ACR, but not 24-hr urinary protein level,was sig-nificantly higher in women with HDCP. There was positive correlation between the ACR and 24-hr urinary protein quantitation. Age, gestational weeks, ACR, red blood cells, fasting plasma glucose, serum creatinine, total pro-tein were the independent risk factors for HDCP. The sensitivity , specificity and optimal cut off value of ACR for predicting HDCP were 0.78, 0.63, 1.46 mg/mmol. Conclusions There was positive correlation between ACR and 24-hr urinary protein quantitation , and ACR provided a more sensitive pathway for early predictionof HDCP.

关键词

高血压,妊娠性/白蛋白尿/肌酸酐/尿分析

Key words

Hypertension/Pregnancy-Induced/Albuminuria/Creatinine, Urinalysis

引用本文复制引用

阴红,高云飞,何淑明,余艳萍,黄启涛,王艳,孔紫靖,钟梅..随机尿白蛋白/肌酐比值对妊娠期高血压疾病的预测价值[J].实用医学杂志,2015,(9):1441-1443,3.

基金项目

中山市科技局立项课题 ()

实用医学杂志

OA北大核心CSTPCD

1006-5725

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