实用医学杂志Issue(11)：1775-1778,4.DOI:10.3969/j.issn.1006-5725.2015.11.015
心脏再同步治疗对慢性心力衰竭患者心功能及心律失常的影响
Effects of cardiac resynchronization therapy on cardiac function and arrhythmia of patients with chronic heart failure
摘要
Abstract
Objective To study the effect of cardiac resynchronization therapy (CRT) on the cardiac function and arrhythmias of patients with chronic heart failure and left ventricular systolic dyssynchrony. Methods Thirty-two cases of patients with chronic heart failure and left ventricular systolic dyssynchrony underwent CRT therapy. And LEVESV, LVEDV, LVEF, LVEDD, MRA, LAA, MRA/LAA were detected by echocardiography while the cardiac function was kept stable. Then the left ventricular systolic 12 segment peak time (Ts) was measurements by tissue doppler in all patients, the poor (Ts-maxD) and standard deviation (Ts-SD) were also calculated. The 24-hour ambulatory 12-lead ECG was took postoperation. All the patients were treated by anti-heart failure drugs after CRT pacemeker implantantion. All these indicators were assessed again at 12 weeks later. Results Compared with the previous CRT pacemaker implantation, LVEF, LV dp/dpsignificantly increased (P < 0.05). LEVESV, Ts-maxD, Ts-SD, MRA, MRA/LAA markedly declined (P < 0.05). But no statistical significance was found between the preoperative and postoperative CRT (P>0.05). Atrial premature beats and paroxysmal atrial tachycardia were significantly reduced in the preoperative CRT (P < 0.05). No significant differences were found in atrial fibrillation, ventricular premature beats and paroxysmal supraventricular tachycardia between the preoperative and postoperative CRT (P > 0.05). Conclusion CRT resynchronization therapy can improve left ventricular systolic function, and reduce the MRA and Ts. The mechanism may be associated with the improvement of left ventricular synchrony, reducing mitral regurgitation, and reducing the occurrence of atrial arrhythmias.关键词
心律失常/心脏再同步治疗/慢性心力衰竭/心功能Key words
cardiac resynchronization therapy/chronic heart failure/heart function/arrhythmia引用本文复制引用
曾智桓,陈泗林,赵艳群,周万兴,张卫,肖月琼,郑坚奕,周玉良..心脏再同步治疗对慢性心力衰竭患者心功能及心律失常的影响[J].实用医学杂志,2015,(11):1775-1778,4.基金项目
广东省科技基金立项资助 （）
