实用医学杂志Issue(11)：1786-1789,4.DOI:10.3969/j.issn.1006-5725.2015.11.019
经皮射频消融联合化疗治疗Ⅲb～Ⅳ期非小细胞肺癌的疗效
Curative effect of radiofrequency ablation combined with chemotherapy on middle-late stage non-small cell lung cancer
摘要
Abstract
Objective To observe the clinical curative effect of Ⅲb~Ⅳstage non-small cell lung cancer treated by radiofrequency ablation combined with chemotherapy. Methods Forty-eight Ⅲb~Ⅳstage non-small cell lung cancer patients were divided into the study group (RFA + chemotherapy) and 74 were in control group (chemotherapy alone) by the method of non randomized controlled. Curative effect was evaluated every two cycles during the treatment. A 6 to 36 months follow-up was conducted after the treatment. Results The objective response rate of experiment group and control group was 58.3%and 41.9%respectively (P>0.05) with no significant difference and disease control rates of experiment group and control group were 91.7% and 75.7% respectively (P<0.05). MST were 14.4 months and 8.2 months respectively (P<0.01), with statistically significant differences in experiment group and control group and clinical benefit efficient were 87 . 5% and 66 . 2% respectively ( P < 0.05). Conclusion The treatment of radiofrequency ablation combined with chemotherapy for advanced non-small cell lung cancer can significantly improve the patient′s survival and the clinical curative effect.关键词
癌,非小细胞肺/射频消融/化疗Key words
Non-small cell lung cancer/Radiofrequency ablation/Chemotherapy引用本文复制引用
周京旭,李虹,吕文姣,王树堂,郑心婷,林丽珠..经皮射频消融联合化疗治疗Ⅲb～Ⅳ期非小细胞肺癌的疗效[J].实用医学杂志,2015,(11):1786-1789,4.基金项目
广东省科技计划项目（编号2012B031800207）；广东省中医药管理局课题 （）
