实用医学杂志Issue(12)：1942-1944,3.DOI:10.3969/j.issn.1006-5725.2015.12.013
石河子市社区高血压患者血清钙／钙调蛋白依赖性蛋白激酶Ⅳ水平的相关性
Correlation between the level of Ca2+/calmodulin-dependent protein kinases IV and essential hypertension in Shihezi community
摘要
Abstract
Objective To study the correlation between the level of CaMKIV and essential hypertension (EH) in Shihezi community. Methods One hundred and forty-six patients with EH and 142 with normal blood pressure are enrolled from 15 communities in shihezi. We collected the clinical data, including blood pressure, body mass index, waist circumference, blood lipids. The serum level of CaMKIV was detected using an enzyme linked immunosorbent assay. Results The serum level of CaMKIV in the EH group was significantly lower than that in the normal blood pressure group (P < 0.05). The serum CaMKIV was negatively correlated with systolic BP and diastolic BP (r = -0.304, -0.452, all P < 0.05), with more obvious correlation with patients whose diastolic blood pressure was over 100 mmHg (r = -0.571, P < 0.05). Conclusions The serum level of CaMKIV is negatively correlated with EH, which is an independent factor of EH.关键词
高血压,原发性/钙调蛋白依赖性蛋白激酶Ⅳ/社区Key words
Essential Hypertension/Ca2+/calmodulin-dependent protein kinasea Ⅳ/Community引用本文复制引用
王忠,陈少泽,赵若飞,杨军,王丽,翟志红,任宏强,郑丽华..石河子市社区高血压患者血清钙／钙调蛋白依赖性蛋白激酶Ⅳ水平的相关性[J].实用医学杂志,2015,(12):1942-1944,3.基金项目
石河子大学重大科技攻关计划 （）
