实用医学杂志Issue(13)：2182-2185,4.DOI:10.3969/j.issn.1006-5725.2015.13.037
鸦胆子油乳注射液联合放疗治疗食管癌的Meta分析
Meta-analysis of javanica oil emulsion injection combined with radiotherapy in the treatment of esophageal carcinoma
陈剑 1李路路 1张鼎儒 1郭宇飞 1郭新成1
作者信息
- 1. 454001 河南省焦作市第二人民医院放疗科
- 折叠
摘要
Abstract
Objective To evaluate the advantage and clinical value of javanica oil emulsion injection combined with radiotherapy for esophageal carcinoma. Method Randomized controlled trials (RCTs) concerning javanica oil emulsion injection combined with radiotherapy for esophageal carcinoma were made on electronic databases of CBM, CNKI, Wangfang, VIP and PubMed from 1990 to February 28, 2015. Quality of the included RCTs was assessed by Jadad scoring , and Meta-analyses were performed by RevMan5.3 software. Results Seven RCTs involving 575 patients were included in Meta-analysis. All studies were in low quality. The results of Meta-analyses showed that Javanica oil emulsion injection combined with radiotherapy for esophageal carcinoma, compared with control groups, could increase the recent curative effect (P < 0.000 01) and improve the quality of live (P = 0.000 8), decrease the hematologic toxicities (P = 0.03) and the incidence rate of radioaction esophagitis (P = 0.02), but not enough evidence was found to prove that it can enhance survival rate (P = 0.25). Conclusions The results of Meta-analysis indicate that javanica oil emulsion injection may have therapeutic effects on the treatment of esophageal carcinoma. Yet the effects of javanica oil emulsion injection still need to be confirmed by large multi-center randomized controlled trials.关键词
食管癌/鸦胆子油乳注射液/放射治疗/Meta分析Key words
Javanica oil emulsion injection/Esophageal carcinoma/Radiotherapy/Meta-analysis引用本文复制引用
陈剑,李路路,张鼎儒,郭宇飞,郭新成..鸦胆子油乳注射液联合放疗治疗食管癌的Meta分析[J].实用医学杂志,2015,(13):2182-2185,4.
