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吸收促进剂对人参糖蛋白肠道吸收的影响

陈英红 王颖 姜翔之 罗浩铭

特产研究Issue(2):12-14,56,4.
特产研究Issue(2):12-14,56,4.

吸收促进剂对人参糖蛋白肠道吸收的影响

Effects of Absorption Enhancers on Intestinal Absorption of Glycoprotein from Panax ginseng

陈英红 1王颖 1姜翔之 2罗浩铭3

作者信息

  • 1. 吉林省中医药科学院,长春 130012
  • 2. 吉林大学中日联谊医院,长春 130021
  • 3. 长春中医药大学,长春 130117
  • 折叠

摘要

Abstract

The aim of the present study is to study the intestinal absorption characteristics of PGG in the presence of absorption enhancers and to determine the best site of intestinal PGG absorption .The effects of five absorption enhancers including chitosan ,SDCh ,sodium caprate ,SDS and lecithin on intestinal absorption of PGG is performed by using the gut sac experiments rats in a vitro transepithelial system .The results demonstrated that absorption enhancers could improve the absorption efficiency of PGG in the duodenum ,jejunum ,colon and ileum .The order of enhanced absorption efficiency for duodenal permeation was chitosan>SDCh>sodium caprate>SDS> lecithin and that for colonic was chi-tosan>sodium caprate>SDCh>SDS> lecithin .Duodenum is found to be the best site of absorption .Chitosan is the best of absorption en-hancers of PGG in the current study .

关键词

人参糖蛋白/吸收促进剂/肠道吸收

Key words

PGG(glycoprotein from Panax ginseng)/absorption enhancers/intestinal absorption

分类

医药卫生

引用本文复制引用

陈英红,王颖,姜翔之,罗浩铭..吸收促进剂对人参糖蛋白肠道吸收的影响[J].特产研究,2015,(2):12-14,56,4.

基金项目

国家自然基金项目(81473326);吉林省科技发展计划项目 ()

特产研究

OACSTPCD

1001-4721

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