天津中医药Issue(2)：93-97,5.DOI:10.11656/j.issn.1672-1519.2015.02.08
探讨益肝降脂方对大鼠酒精性脂肪肝病理影响与疗效的相关性
Investigation on the correlation of the effect of Yigan Jiangzhi Fang on Pathology in rats with alcoholic fatty liver
摘要
Abstract
Objective] To observe the morphological changes of liver tissue in order to discuss and verify the pathology effects on liver tissue of Yigan Jiangzhi Fang (YGJZF) on alcoholic fatty liver in rats. [Methods] The experiments were divided into 3 stages. A total of 275 male SD rats were randomly divided into 3 groups:blank group 15, model group 50, YGJZF group 180. Rats were given fat diet and alcohol feeding to establish alcoholic fatty liver model, and were separately corresponding intervention, rats in each group were stained with HE to make pathological slices at the same position of liver tissue, observed the changes of morphological liver tissue of three groups of rats. [Results] The degree of rats liver tissue injury in YGJZF group was lighter than in the model group, and the difference was statistically significant. [Conclusion] YGJZF can reduce the pathological injury of liver tissue of alcoholic fatty liver in rats, has a positive protection effect on alcoholic fatty liver.关键词
益肝降脂方/酒精性脂肪肝/肝组织病理Key words
Yigan Jiangzhi Fang/alcoholic fatty liver/hepatic tissue pathology分类
医药卫生引用本文复制引用
李全征,赵远红,李正,贾英杰,左晓娜,韩素恒,徐雨,尹纪红..探讨益肝降脂方对大鼠酒精性脂肪肝病理影响与疗效的相关性[J].天津中医药,2015,(2):93-97,5.基金项目
天津市应用基础及前沿技术重点项目（11JCZD JC19900）。 （）
