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正交实验优化独活总香豆素的渗漉提取工艺

王春鹏 罗倩 李晋 何俊 马文芳 刘二伟 常艳旭

天津中医药Issue(2):113-116,4.
天津中医药Issue(2):113-116,4.DOI:10.11656/j.issn.1672-1519.2015.02.13

正交实验优化独活总香豆素的渗漉提取工艺

OPtimization orthogonal of Percolation extraction Process of Radix Angelicae pubescentis coumarin

王春鹏 1罗倩 1李晋 1何俊 1马文芳 1刘二伟 1常艳旭1

作者信息

  • 1. 天津市现代中药重点实验室,天津中医药大学,天津 300193
  • 折叠

摘要

Abstract

Objective] To investigate the best percolation extraction condition of Radix Angelicae Pubescent coumarin. [Methods] L9 (37) orthogonal experimental method was used to study the effects of ethanol concentration, solid-liquid ratio, soaking time on the contents of osthole, columbianetin acetate, columbianetin and columbianadin in Radix Angelicae Pubescent extract. [Results] Ethanol concentration was the main factor of affecting percolation,and the optimum extraction was 75% ethanol,solid-liquid ratio of 1∶8,soak 8 hours. [Conclusion] This method could be used as the best percolation extraction process of Radix Angelicae Pubescentis coumarin.

关键词

独活/渗漉提取/正交实验/HPLC

Key words

Radix Angelicae Pubescentis/percolation/orthogonal test/HPLC

分类

医药卫生

引用本文复制引用

王春鹏,罗倩,李晋,何俊,马文芳,刘二伟,常艳旭..正交实验优化独活总香豆素的渗漉提取工艺[J].天津中医药,2015,(2):113-116,4.

基金项目

高等学校博士学科点专项科研基金资助项目(20101210120007)。 ()

天津中医药

OACSTPCD

1672-1519

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