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银杏叶提取物对家兔高胆固醇血症模型脑组织形态学的影响

高青 马东明 胡先同 卢斌 张瑞峰 冯玉陶 姜希娟

天津中医药Issue(3):165-167,3.
天津中医药Issue(3):165-167,3.DOI:10.11656/j.issn.1672-1519.2015.03.09

银杏叶提取物对家兔高胆固醇血症模型脑组织形态学的影响

Effect of the extract of Ginkgo Biloba in brain tissue morphology in rabbit hypercholesteremia model

高青 1马东明 1胡先同 1卢斌 1张瑞峰 2冯玉陶 3姜希娟1

作者信息

  • 1. 天津中医药大学中西医结合学院,天津 300193
  • 2. 新泰市中医院病理科,新泰 271200
  • 3. 天津武警后勤学院附属医院中医科,天津 300162
  • 折叠

摘要

Abstract

Objective] To study the effect of the extract of Ginkgo Biloba 761 (EGB 761) on brain tissue morphology in rabbit hyperc-holesteremia model. [Methods] We built the hypercholesteremia model with male New Zealand white rabbits, which were divided into four groups:the control group, the model group, the simvastatin group, the EGB761 group. Detecting the morphology change of nerve fiber with HE staining and silver staining. [Results] The hippocampus in model group showed neuronal degeneration, necrosis and microfibers tangles while the EGB761 group showed less neuronal degeneration, necrosis and microfibers tangles, and regular nuclear morphometry. [Conclusion] EGB761 can effectively protect the integrity of the structure of nerve fibers in hypercholesterolemia.

关键词

银杏叶提取物/高胆固醇血症/神经纤维

Key words

extract of Ginkgo Biloba/hypercholesteremia/nerve fiber

分类

医药卫生

引用本文复制引用

高青,马东明,胡先同,卢斌,张瑞峰,冯玉陶,姜希娟..银杏叶提取物对家兔高胆固醇血症模型脑组织形态学的影响[J].天津中医药,2015,(3):165-167,3.

基金项目

资金项目高校博士点专项基金资助项目(20101210120008)。 ()

天津中医药

OACSTPCD

1672-1519

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