无机材料学报2015，Vol.30Issue(5)：516-522,7.DOI:10.15541/jim20140528
电纺制备明胶/壳聚糖/羟基磷灰石/氧化石墨烯抗菌复合纳米纤维的研究
Electrospinning Gelatin/Chitosan/Hydroxyapatite/Graphene Oxide Composite Nanofibers with Antibacterial Properties
摘要
Abstract
Gelatin/chitosan/hydroxyapatite/graphene oxide composite nanofibers were prepared by electrospinning. The effect of composition on fiber morphology and antibacterial properties were investigated. The results show that increasing of gelatin concentration results in the increase of fiber diameter and then heavy fiber adhesion, showing ideal concentration scope of 15%-20%. Increasing chitosan concentration leads to thin fibers, with optimum concen-tration at 1%, while increasing hydroxyapatite (HA) concentration increases the ionic concentration of eletrospinning solution, leading to the decrease of beads and fiber adhesion. Nanofibers with smooth morphology are obtained when the diameter of HA particles is 12μm and at concentration of 5%. And the addition of graphene oxide (GO) enhances uniform, smooth and antibacterial property of the composite nanofibers, which enables the gelatin/chitosan/hydrox- yapatite/GO fibers good antibacterial effect against bothStaphylococcus aureus andEscherichia coli.关键词
壳聚糖/羟基磷灰石/氧化石墨烯/电纺纤维/抗菌率Key words
gelatin/chitosan/hydroxyapatite/graphene oxide/electrospun fibers/antibacterial property分类
化学化工引用本文复制引用
梁红培,王英波,粟智,鲁雄,王帅..电纺制备明胶/壳聚糖/羟基磷灰石/氧化石墨烯抗菌复合纳米纤维的研究[J].无机材料学报,2015,30(5):516-522,7.基金项目
新疆维吾尔自治区高校科研计划(XJEDU2011S32) （XJEDU2011S32）
新疆师范大学博士科研启动基金(xjnubs1102) （xjnubs1102）
自治区引进高层次紧缺人才启动经费 （）
新疆师范大学无机化学重点学科建设项目(13XSXZ0702) Scientific Research Program of the Higher Education Institution of Xinjiang (XJEDU2011S32) （13XSXZ0702）
Scientific Research Staring Foundation for Doctor of Xinjiang Normal University (xjnubs1102) （xjnubs1102）
High Level Short of Talent Starting Funds from the Autonomous Regions （）
Inorganic Chemistry Key Subject Construction Project of Xinjiang Normal University (13XSXZ0702) （13XSXZ0702）
