武警医学Issue(7)：690-692,697,4.
射频消融术治疗骨转移瘤回顾性研究
Radiofrequency ablation for treatment of bone metastases:a retrospective study
李伟 1曹亮 2盛俊 1幺建立 1彭勋 1彭勇3
作者信息
- 1. 066000，河北省秦皇岛市第三医院肿瘤科
- 2. 450000，郑州市人民医院颐和医院肿瘤科
- 3. 066004，秦皇岛燕山大学生物医学工程系
- 折叠
摘要
Abstract
Objective To evaluate the clinical therapeutic effects of bone radiofrequency ablation on patients with bone metas -tases from hepatocellular carcinoma ,lung cancer and breast cancer .Methods To retrospectively analyze 22 hepatocellular carcinoma patients,12 lung cancer patients and 8 breast cancer patients with bone metastases who received radiofrequency ablation at Qinhuangdao No.3 hospital.The mean diameter of the bone metastases was 3.8 cm (range, 1.0-5.5 cm).The integrality,practicability and safety of this procedure were reviewed .The pain relief and of the bone metastases the quality of life were observed before RFA , as well as 1 week after and 1 month after RFA.NRS(numerical rating scale) was used to determine pain level, KPS(Karnofsky) was used to grade functional status.Patients’ quality of life was scored by using EORTC QLQ-C30 system.Results 42 cases (100%) completed RFA successfully.11(26.2%) cases exhibited worse pain levels within the first week after RFA .However, pains were all relieved signifi-cantly after 1 month (P<0.001).KPS increased dramatically from(74.05 ±11.92)to(88.64 ±6.28) before the RFA treatment and after 1 month of it(P<0.05).EORTC QLQ-C30 scores were also improved significantly , with (85.50 ±8.59) scores before RFA, and 60.88 ±9.5 and 51.38 ±7.48 within 1 week and 1 month ,respectively.Patients’ quality of life increased remarkably ( P<0.05).Conclusions Bone radiofrequency ablation is efficient and safe in the treatment of bone metastases , especially the pain, pa-tients’ life of quality and functional statues that caused by bone metastases were improved dramatically .关键词
射频消融术/骨转移瘤/骨疼痛/生活质量Key words
radiofrequency ablation/bone metastases/bone pain/quality of life分类
医药卫生引用本文复制引用
李伟,曹亮,盛俊,幺建立,彭勋,彭勇..射频消融术治疗骨转移瘤回顾性研究[J].武警医学,2014,(7):690-692,697,4.
