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正清风痛宁片治疗 IgA肾病中等量蛋白尿的疗效

王文 高德 祖静 贺晓

武警医学Issue(10):1021-1023,1028,4.
武警医学Issue(10):1021-1023,1028,4.

正清风痛宁片治疗 IgA肾病中等量蛋白尿的疗效

Efficacy of Zhengqiang Fengtongning Tablets in the treatment of IgA nephropathy with moderate amount of proteinuria

王文 1高德 1祖静 1贺晓1

作者信息

  • 1. 116013,武警辽宁总队大连医院门诊部
  • 折叠

摘要

Abstract

Objective To study the safety and efficacy of Zhengqiang Fengtongning Tablets in the treatment of IgA nephropa-thy with moderate amount of proteinuria.Methods 156 patients with IgA nephropathy with moderate amount of proteinuria ( urine pro-tein quantitation:1-3 g/24 h) were randomly divided into two groups.The study group was given Zhengqiang Fengtongning Tablets with valsartan and control group was given valsartan alone for treatment.The dosage of Zhengqiang Fengtongning was 2 tablets, 3 times a day, and valsartan was 80 mg/day.Results After treatment for 6 months, the total effective rate in the study group was significantly higher than that in the control group( 87.2%vs 56.4%, P<0.01).24 h urinary protein in the study group was significantly lower than that in the control group(1.59 ±0.66, P<0.05).There were no differences in serum albumine, serum creatinine (Scr) , total protein ( TP) , total cholesterol ( TC) , and incidence of adverse reactions between the two groups.Conclusions Zhengqiang Feng-tongning Tablets combined with valsartan for the treatment of IgA nephropathy with moderate amount of proteinuria is safe and reliable, which is worthy of clinical application.

关键词

IgA肾病/正清风痛宁片/缬沙坦

Key words

IgA nephropathy/Zhengqiang Fengtongning Tablets/valsartan

分类

医药卫生

引用本文复制引用

王文,高德,祖静,贺晓..正清风痛宁片治疗 IgA肾病中等量蛋白尿的疗效[J].武警医学,2014,(10):1021-1023,1028,4.

武警医学

OACSTPCD

1004-3594

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